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DUSP1 anticorps (N-Term)

DUSP1 Reactivité: Humain WB, EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN360822
  • Antigène Voir toutes DUSP1 Anticorps
    DUSP1 (Dual Specificity Phosphatase 1 (DUSP1))
    Épitope
    • 17
    • 15
    • 7
    • 7
    • 7
    • 6
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 84
    • 35
    • 34
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 80
    • 3
    • 1
    Lapin
    Clonalité
    • 73
    • 11
    Polyclonal
    Conjugué
    • 28
    • 7
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp DUSP1 est non-conjugé
    Application
    • 63
    • 37
    • 27
    • 26
    • 14
    • 11
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Specificité
    This antibody reacts to DUSP1.
    Purification
    Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
    Immunogène
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human DUSP1.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product DUSP1 Anticorps primaire
  • Indications d'application
    ELISA: 1/1,000. Western blotting: 1/100 - 1/500.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Antigène
    DUSP1 (Dual Specificity Phosphatase 1 (DUSP1))
    Autre désignation
    DUSP1 / MKP1 (DUSP1 Produits)
    Synonymes
    anticorps CL100, anticorps HVH1, anticorps MKP-1, anticorps MKP1, anticorps PTPN10, anticorps 3CH134, anticorps Mkp1, anticorps Ptpn16, anticorps DUSP1, anticorps U19515, anticorps erp, anticorps mkp-1, anticorps cb269, anticorps sb:cb269, anticorps zgc:55920, anticorps id:ibd2586, anticorps wu:fd19g02, anticorps wu:fe50g09, anticorps XCL100, anticorps dual specificity phosphatase 1, anticorps dual specificity phosphatase 1 S homeolog, anticorps DUSP1, anticorps Dusp1, anticorps dusp1, anticorps dusp1.S
    Sujet
    The expression of DUSP1 gene is induced in human skin fibroblasts by oxidative/heat stress and growth factors. It specifies a protein with structural features similar to members of the non-receptor-type protein-tyrosine phosphatase family, and which has significant amino-acid sequence similarity to a Tyr/Ser-protein phosphatase encoded by the late gene H1 of vaccinia virus. The bacterially expressed and purified DUSP1 protein hasintrinsic phosphatase activity, and specifically inactivates mitogen-activated protein (MAP) kinase in vitro by the concomitant dephosphorylation of both its phosphothreonine and phosphotyrosine residues. Furthermore, it suppresses the activation of MAP kinase by oncogenic ras in extracts of Xenopus oocytes. Thus, DUSP1 may play an important role in the human cellular response to environmental stress as well as in the negative regulation of cellular proliferation.Synonyms: CL100, Dual specificity protein phosphatase 1, Dual specificity protein phosphatase hVH1, MAP kinase phosphatase 1, MKP-1, PTPN10, Protein-tyrosine phosphatase CL100, VH1
    ID gène
    1843, 9606
    UniProt
    P28562
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