anti-14-3-3 epsilon (YWHAE) anticorps

Aperçu

» Cliquez pour enlarger
	Antigène:	14-3-3 epsilon (YWHAE)
	Clonalité:	Monoclonal (5A5)
	Application:	ELISA, Western Blotting (WB)
	Reactivité:	Human
	Hôte:	Mouse
	Quantité:	100ul (1mg/ml) (Alternatives)
	Prix:	334,99 € (Plus frais de livraison et TVA)
	Numéro du produit:	ABIN361177
	Disponibilité:	Envoi sous 5 à 10 jours ouvrables

Antigène	14-3-3 epsilon (YWHAE)
Immunogène	Recombinant human 14-3-3 epsilon (1-255aa), Accession / GI number: NP_006752
Reactivité	Human
Clonalité	Monoclonal
Isotype	IgG2a, k »Anticorps secondaires correspondants
Description	The 14-3-3 family of proteins plays a key regulatory role in signal transduction, checkpoint control, apoptotic and nutrient-sensing pathways. 14-3-3 proteins are highly conserved and ubiquitously expressed. There are at least seven isoforms, beta, gamma, epsilon, sigma, zeta, tau and eta that have been identified in mammals. The 14-3-3 epsilon, a subtype of the 14-3-3 family of proteins, was thought to be brain and neuron-specific. It has been shown to interact with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. Synonyms: 14-3-3 epsilon
Clone	5A5
Hôte	Mouse

Application	ELISA, Western Blotting (WB)
Indications d'application	Recommended dilution 1:1000
Concentration	1mg/ml
Purification	The antibody was purified from mouse ascitic fluids by protein-G affinity chromatography
Buffer	In Phosphate-Buffered Saline (pH7.4) with 0.1% Sodium Azide
Stock	Store at -20°, Aliquot to avoid repeated freezing and thawing.
Domaine de recherche	Cancer
Restrictions	For Research Use only