SEMA4D/CD100 anticorps

N° du produit ABIN361535

Détail du produit anti-SEMA4D/CD100 anticorps

Antigène: SEMA4D/CD100 (SEMA4D) (Sema Domain, Immunoglobulin Domain (Ig), Transmembrane Domain (TM) and Short Cytoplasmic Domain, (Semaphorin) 4D (SEMA4D))

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SEMA4D/CD100 est non-conjugé

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), ELISA

Purification: ProteinG Affinity Purified

Immunogène: Recombinant protein of Mouse Semaphorin 4D (extracellular domain)

Clone: SK-3

Isotype: IgG1 kappa

Information d'application

Indications d'application: ELISA: 1-10ug/ml. IP: 5ug/ml. FACS: 0.05ug/ml

Restrictions: For Research Use only

Stockage

Concentration: 0.25 mg/ml

Buffer: PBS [containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat]

Agent conservateur: ProClin

Stock: -20 °C

Détails sur SEMA4D/CD100

Antigène: SEMA4D/CD100 (SEMA4D) (Sema Domain, Immunoglobulin Domain (Ig), Transmembrane Domain (TM) and Short Cytoplasmic Domain, (Semaphorin) 4D (SEMA4D))

Autre désignation: Semaphorin 4D (SEMA4D Produits)

Synonymes: anticorps C9orf164, anticorps CD100, anticorps M-sema-G, anticorps SEMAJ, anticorps coll-4, anticorps Semacl2, anticorps Semaj, anticorps Semcl2, anticorps COLL-4, anticorps semaphorin 4D, anticorps sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D, anticorps Sema4d, anticorps SEMA4D

Sujet: Semaphorins are a family of phylogeneticallyconserved soluble and transmembrane proteins. Semaphorins were originally identified as axon guidance factors during neuronal development.Semaphorins are now known to be widely expressed mediators that play significantroles in immune responses and organ morphogenesis. Sema4D (also known as CD100) is a 150-kDa transmembrane protein of the class IV semaphorin subfamily. Sema4D is expressed at high levels in lymphoid organs, including the spleen, thymus, and lymph nodes, and in non-lymphoidorgans, such as the brain, heart, andkidney. In lymphoid organs, Sema4D is expressed abundantly by T cells but weakly by B cells. Its expression is significantly enhanced inboth T and B cells, following their respective activation. Sema4D is proteolyticallycleaved from their transmembrane form to generate 120-kDa soluble forms. Two types of receptors, Plexin-B1 and CD72, have been identified for soluble Sema4D.

ID gène: 20354

Pathways: Regulation of Cell Size