DNAJB1 anticorps

N° du produit ABIN361660

Détail du produit anti-DNAJB1 anticorps

Antigène: DNAJB1 (DnaJ (Hsp40) Homolog, Subfamily B, Member 1 (DNAJB1))

Reactivité: Saccharomyces cerevisiae

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp DNAJB1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Specificité: Detects ~40 kDa. Yeast specific product. Does not cross react with Human, Mouse or Rat.

Réactivité croisée: Saccharomyces cerevisiae

Purification: Protein G Purified

Immunogène: Full length protein yeast HSP40 (YDJ1)

Clone: 1G10-H8

Isotype: IgG1 kappa

Information d'application

Indications d'application:

• WB (1:2000)
• optimal dilutions for assays should be determined by the user.

Commentaires:

0.5 μg/ml of ABIN361659 was sufficient for detection of 50 ng YDJ1 by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: -20°C

Détails sur DNAJB1

Antigène: DNAJB1 (DnaJ (Hsp40) Homolog, Subfamily B, Member 1 (DNAJB1))

Autre désignation: HSP40 (DNAJB1 Produits)

Synonymes: anticorps HSPF1, anticorps Hdj1, anticorps Hsp40, anticorps RSPH16B, anticorps Sis1, anticorps CG10578, anticorps DNAJ-1, anticorps DNAJ1, anticorps DROJ1, anticorps Dmel\\CG10578, anticorps DnaJ1 64EF, anticorps DroJ1, anticorps EU3500, anticorps HSP40, anticorps HSP40/HDJ1, anticorps Hsp-40, anticorps anon-WO0140519.166, anticorps anon-WO0172774.135, anticorps dHDJ1, anticorps dHDJ1/HSP40, anticorps dHdj1, anticorps dhdJ1, anticorps dhdj-1, anticorps dhdj1, anticorps dnaJ-1, anticorps droj1, anticorps hsp40, anticorps dnajb4, anticorps hdj1, anticorps hspf1, anticorps sis1, anticorps DnaJ-5, anticorps MAS5, anticorps dnaJ, anticorps 0610007I11Rik, anticorps dnajb1, anticorps zf-Hsp40, anticorps zgc:101068, anticorps DnaJ heat shock protein family (Hsp40) member B1, anticorps DnaJ-like-1, anticorps DnaJ (Hsp40) homolog 5, anticorps type I HSP40 co-chaperone YDJ1, anticorps DnaJ protein, anticorps molecular chaperone DnaJ, anticorps DnaJ (Hsp40) homolog, subfamily B, member 1a, anticorps DNAJB1, anticorps Dnajb1, anticorps DnaJ-1, anticorps dnajb1, anticorps DnaJ-5, anticorps YDJ1, anticorps dnaJ, anticorps dnajb1a

Sujet: Human HSP40/DnaJ proteins comprise a large protein family, members of which feature the J domain (named after the bacterial DnaJ protein) (1). The J-domain spans the first 75 N-terminal amino acids and is separated from the C-terminal by a glycine/phenylalanine-rich domain (2). There are two main types of HSP40, type 1 DNAJ proteins including HDJ2 and yeast YdjI, type II includes yeast Sis1 and human Hdj1. Whereas type I possesses a zinc finger domain which helps in the function of protein folding. (3, 4), type II does not. Members of the HSP40/DnaJ family play diverse roles in many cellular processes, such as folding, translocation, degradation and assembly of multi-protein complexes. HSP40 stimulates the ATPase activity of HSP70 which in turn causes conformational changes of the unfolded proteins (5, 6). The HSP40-HSP70-unfolded protein complex further binds to co-chaperones Hip, Hop and HSP90 which leads to protein folding, or components of protein degradation machinery CHIP and BAG-1 (7).

ID gène: 855661

NCBI Accession: NP_014335

UniProt: P25491