DNAJB1 anticorps (C-Term)

N° du produit ABIN361684

Détail du produit anti-DNAJB1 anticorps

Antigène: DNAJB1 (DnaJ (Hsp40) Homolog, Subfamily B, Member 1 (DNAJB1))

Épitope: C-Term

Reactivité: Plasmodium falciparum

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DNAJB1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: Detects ~ 62 kDa. Specific to P. Falciparum and does not cross-react to any protein from Human erythrocytes.

Réactivité croisée: Plasmodium falciparum

Purification: Protein A Purified

Immunogène: C-terminal peptide of Pf11_0513 conjugated to KLH

Information d'application

Indications d'application:

• WB (1:2000)
• ICC/IF (1:50)
• optimal dilutions for assays should be determined by the user.

Commentaires:

0.9 μg/ml of ABIN361684 was sufficient for detection of Pf11_0513 in 20 μg of P. falciparum lysate by colorimetric immunoblot analysis using Goat anti-rabbit IgG:HRP as the secondary antibody.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.8 mg/mL

Buffer: PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: -20°C

Détails sur DNAJB1

Antigène: DNAJB1 (DnaJ (Hsp40) Homolog, Subfamily B, Member 1 (DNAJB1))

Autre désignation: HSP40 (DNAJB1 Produits)

Synonymes: anticorps HSPF1, anticorps Hdj1, anticorps Hsp40, anticorps RSPH16B, anticorps Sis1, anticorps CG10578, anticorps DNAJ-1, anticorps DNAJ1, anticorps DROJ1, anticorps Dmel\\CG10578, anticorps DnaJ1 64EF, anticorps DroJ1, anticorps EU3500, anticorps HSP40, anticorps HSP40/HDJ1, anticorps Hsp-40, anticorps anon-WO0140519.166, anticorps anon-WO0172774.135, anticorps dHDJ1, anticorps dHDJ1/HSP40, anticorps dHdj1, anticorps dhdJ1, anticorps dhdj-1, anticorps dhdj1, anticorps dnaJ-1, anticorps droj1, anticorps hsp40, anticorps dnajb4, anticorps hdj1, anticorps hspf1, anticorps sis1, anticorps DnaJ-5, anticorps MAS5, anticorps dnaJ, anticorps 0610007I11Rik, anticorps dnajb1, anticorps zf-Hsp40, anticorps zgc:101068, anticorps DnaJ heat shock protein family (Hsp40) member B1, anticorps DnaJ-like-1, anticorps DnaJ (Hsp40) homolog 5, anticorps type I HSP40 co-chaperone YDJ1, anticorps DnaJ protein, anticorps molecular chaperone DnaJ, anticorps DnaJ (Hsp40) homolog, subfamily B, member 1a, anticorps DNAJB1, anticorps Dnajb1, anticorps DnaJ-1, anticorps dnajb1, anticorps DnaJ-5, anticorps YDJ1, anticorps dnaJ, anticorps dnajb1a

Sujet: DnaJ/HSP40 proteins have been preserved throughout evolution and are important for protein translation, folding, unfolding, translocation, and degradation, primarily by stimulating the ATPase activity of chaperone proteins, HSP70s. Because the ATP hydrolysis is essential for the activity of HSP70s, DnaJ/HSP40 proteins actually determine the activity of HSP70s by stabilizing their interaction with substrate proteins. DnaJ/HSP40 proteins all contain the J domain through which they bind to HSP70s. HSP40, also known as HDJ1 (1), is a basic mammalian 40 kDa heat shock protein which is not only homologous to the bacterial heat shock protein (DnaJ), but also yeast DnaJ-related proteins such as SCJ1, Sec63/Npl1, YDJ1 and SIS1 (2-6). HSP 40 is inducible by stress including heat after which is moves from the cytoplasm to the nucleus and nucleoli, an intracellular pattern similar to HSC70/HSP70, the mammalian homologues of the bacterial heat shock protein, DnaK (3). PF11_0513 belongs to the HSP40 family of chaperones. This protein has a Plasmodium export element (PEXEL). It is exported out of the parasite into the infected erythrocytic compartment.

ID gène: 811046

NCBI Accession: XP_001348169

UniProt: Q8IHM7