ErbB2/Her2 anticorps (pTyr1221, pTyr1222)
Aperçu rapide pour ErbB2/Her2 anticorps (pTyr1221, pTyr1222) (ABIN362017)
Antigène
Voir toutes ErbB2/Her2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- pTyr1221, pTyr1222
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Specificité
- The antibody detects endogenous level of HER2 only when phosphorylated at tyrosine1221/tyrosine1222.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removedby chromatogramphy using non-phosphopeptide corresponding to the phosphorylation site.
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Immunogène
- Peptide sequence around phosphorylation site of pTyr1221, pTyr1222 (N-L-Y (p) -Y (p) -W) derived from Human HER2. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
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Isotype
- IgG
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anti-Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2) (AA 23-372) antibody
ErbB2/Her2 Reactivité: Humain WB, IHC, IP, ICC Hôte: Lapin Polyclonal unconjugated
anti-Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2) (C-Term) antibodyErbB2/Her2 Reactivité: Humain, Souris, Rat, Chien, Singe, Cheval, Porc, Lapin, Boeuf (Vache), Hamster, Avian, Cat, Poulet, Âne, Chévre, Cobaye, Mouton WB, IHC (p), IHC (fro) Hôte: Chèvre Polyclonal unconjugated
anti-Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2) (pTyr1248) antibodyErbB2/Her2 Reactivité: Humain, Souris, Rat WB, IHC, IF, ELISA, ICC Hôte: Lapin Polyclonal unconjugated
anti-Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2) (pTyr877) antibodyErbB2/Her2 Reactivité: Humain, Souris, Rat WB, IHC, IF, ELISA, IP, ICC Hôte: Lapin Polyclonal unconjugated
anti-Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2) (pTyr1112) antibodyErbB2/Her2 Reactivité: Humain, Souris, Rat WB, IHC, IF, ELISA, ICC Hôte: Lapin Polyclonal unconjugated
anti-Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2) (AA 22-121) antibodyErbB2/Her2 Reactivité: Humain WB, IF, ELISA, IHC (p), PLA Hôte: Souris Monoclonal 3B1 unconjugated
anti-Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2) (AA 311-462) antibodyErbB2/Her2 Reactivité: Humain IHC, IF, FACS Hôte: Souris Monoclonal ERBB2-2452 unconjugated
anti-Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2) (AA 311-462) antibodyErbB2/Her2 Reactivité: Humain IHC Hôte: Souris Monoclonal ERBB2-3078 unconjugated
anti-Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2) (AA 1205-1255) antibodyErbB2/Her2 Reactivité: Humain, Souris WB, IHC, FACS, IP, ICC Hôte: Lapin Monoclonal BLR241L unconjugated Recombinant Antibody
anti-Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2) (pTyr1196) antibodyErbB2/Her2 Reactivité: Humain WB, IF, DB Hôte: Lapin Polyclonal RB40085 unconjugated
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Indications d'application
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Western blotting: 1:500-1:1000
Immunofluorescence: 1:100-1:200 -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- ErbB2/Her2 (Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2))
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Autre désignation
- HER2
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Sujet
- Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. Not activated by EGF, TGF-a and amphiregulin.
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Poids moléculaire
- 185 kDa
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NCBI Accession
- NP_001005
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UniProt
- P04626
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Pathways
- Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Skeletal Muscle Fiber Development
Antigène
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