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Cofilin anticorps (pTyr139)

CFL1 Reactivité: Humain, Souris, Rat IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN362440
  • Antigène Voir toutes Cofilin (CFL1) Anticorps
    Cofilin (CFL1) (Cofilin 1 (CFL1))
    Épitope
    • 18
    • 17
    • 16
    • 15
    • 12
    • 11
    • 9
    • 8
    • 8
    • 7
    • 6
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pTyr139
    Reactivité
    • 146
    • 98
    • 93
    • 6
    • 6
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 150
    • 10
    • 2
    Lapin
    Clonalité
    • 150
    • 11
    Polyclonal
    Conjugué
    • 72
    • 12
    • 12
    • 9
    • 8
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    Cet anticorp Cofilin est non-conjugé
    Application
    • 82
    • 73
    • 48
    • 47
    • 41
    • 41
    • 32
    • 30
    • 16
    • 13
    • 8
    • 7
    • 3
    • 3
    • 3
    • 2
    • 1
    Immunohistochemistry (IHC)
    Specificité
    The antibody detects endogenous level of cofilin1 only when phosphorylated at tyrosine 139.
    Purification
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removedby chromatography using non-phosphopeptide corresponding to the phosphorylation site.
    Immunogène
    Peptide sequence around phosphorylation site of pTyr139 (N-C-Y (p) -E-E) derived from Human cofilin. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
    Isotype
    IgG
  • Indications d'application
    Immunohistochemistry: 1:50-1:100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • Antigène
    Cofilin (CFL1) (Cofilin 1 (CFL1))
    Autre désignation
    cofilin1 (CFL1 Produits)
    Synonymes
    anticorps cfl1, anticorps xac1, anticorps xac2, anticorps cfl, anticorps cb86, anticorps sb:cb86, anticorps zgc:56501, anticorps wu:fb18a04, anticorps wu:fk77b03, anticorps 12/8, anticorps ADF, anticorps ADF/cofilin, anticorps Adf, anticorps CG4254, anticorps Cadf, anticorps D-cof, anticorps D61, anticorps Dmel\\CG4254, anticorps T8, anticorps Tsr, anticorps cofilin, anticorps cofilin/ADF, anticorps cofilin/actin depolymerizing factor homolog, anticorps l(2)03101, anticorps l(2)k03101, anticorps l(2)k05633, anticorps l(2)k13409, anticorps ntf, anticorps CFL, anticorps AA959946, anticorps Cof, anticorps CFL1, anticorps cofilin 1 (non-muscle) L homeolog, anticorps cofilin 1 (non-muscle), anticorps cofilin 1 (non-muscle), like, anticorps cofilin 1, anticorps twinstar, anticorps cofilin, anticorps cofilin 1, non-muscle, anticorps Contrafreeloading, anticorps cfl1.L, anticorps cfl1, anticorps cfl1l, anticorps CFL1, anticorps tsr, anticorps COF1, anticorps TSTA_042790, anticorps Cfl1, anticorps CFL
    Sujet
    Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods.
    Poids moléculaire
    19 kDa
    NCBI Accession
    NP_005498
    UniProt
    P23528
    Pathways
    Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus, CXCR4-mediated Signaling Events
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