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p21 anticorps (AA 143-147)
CDKN1A
Reactivité: Humain
WB
Hôte: Lapin
Polyclonal
unconjugated
Détail du produit anti-p21 anticorps
(cache)
Antigène
Voir toutes p21 (CDKN1A) Anticorps
p21 (CDKN1A)
(Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A))
Épitope
Tous les épitopes à travers p21 Anticorps.
AA 143-147
Reactivité
Toutes les réactivités sur p21 Anticorps
Humain
Hôte
Toutes les hôtes sur p21 Anticorps
Lapin
Clonalité
Toutes les clonalités sur p21 Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers p21 Anticorps
Cet anticorp p21 est non-conjugé
Application
Tous les applications à travers p21 Anticorps.
Western Blotting (WB)
Specificité
The antibody detects endogenous level of total p21Cip1 protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogène
Peptide sequence around AA 143-147 (R-Q-T-S-M) derived from Human p21Cip1. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
Isotype
IgG
Top Product
Discover our top product CDKN1A Anticorps primaire
Alternatives
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anti-Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A) (AA 21-100) antibody
CDKN1A
Reactivité: Humain, Souris, Rat, Mouton
WB, ELISA, FACS, IHC (p), IF (cc), IF (p), ICC, IHC (fro)
Hôte: Lapin
Polyclonal
unconjugated
Information d'application
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Indications d'application
Western blotting: 1:500-1:1000
Restrictions
For Research Use only
Stockage
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Format
Liquid
Concentration
1 mg/mL
Buffer
Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C/-20 °C
Stockage commentaire
Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Références pour anticorps anti-p21 (ABIN362755)
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Kanehira, Kikuchi, Ohkouchi, Shibahara, Tode, Santoso, Daito, Ohta, Tamada, Nukiwa : "Targeting lysophosphatidic acid signaling retards culture-associated senescence of human marrow stromal cells. " dans: PLoS ONE , Vol. 7 , Issue 2 , pp. e32185 , (2012 ) (PubMed ).
Détails sur p21
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Antigène
p21 (CDKN1A)
(Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A))
Autre désignation
p21Cip1 (CDKN1A Produits )
Synonymes
anticorps CCND1, anticorps CDKN1A, anticorps CAP20, anticorps CDKN1, anticorps CIP1, anticorps MDA-6, anticorps P21, anticorps SDI1, anticorps WAF1, anticorps p21CIP1, anticorps CDKI, anticorps Cdkn1, anticorps Waf1, anticorps mda6, anticorps p21Cip1, anticorps p21WAF, anticorps Cip1, anticorps UV96, anticorps p21, anticorps cip1, anticorps p16Xic2, anticorps sdi1, anticorps waf1, anticorps cap20, anticorps cdkn1, anticorps mda-6, anticorps p21cip1, anticorps si:ch1073-48m5.2, anticorps KRAS2, anticorps p21ras, anticorps cyclin D1, anticorps cyclin dependent kinase inhibitor 1A, anticorps cyclin-dependent kinase inhibitor 1A (P21), anticorps cyclin-dependent kinase inhibitor 1A, anticorps cyclin-dependent kinase inhibitor 1A L homeolog, anticorps cyclin-dependent kinase inhibitor 1, anticorps KRAS proto-oncogene, GTPase, anticorps CCND1, anticorps CDKN1A, anticorps Cdkn1a, anticorps cdkn1a.L, anticorps cki1, anticorps cdkn1a, anticorps KRAS
Sujet
May be the important intermediate by which p53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage. Binds to and inhibits cyclin-dependent kinase activity, preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression.
Poids moléculaire
21 kDa
UniProt
P38936
Pathways
Signalisation p53 , Signalisation PI3K-Akt , Cycle Cellulaire , AMPK Signaling , Fc-epsilon Receptor Signaling Pathway , EGFR Signaling Pathway , Neurotrophin Signaling Pathway , Mitotic G1-G1/S Phases , DNA Replication , Hepatitis C , Synthesis of DNA , Autophagy
Vus récemment
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