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PAK1 anticorps (AA 210-214)

PAK1 Reactivité: Humain, Rat, Souris WB, IHC, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN362773
  • Antigène Voir toutes PAK1 Anticorps
    PAK1 (P21-Activated Kinase 1 (PAK1))
    Épitope
    • 34
    • 17
    • 15
    • 13
    • 10
    • 10
    • 9
    • 9
    • 8
    • 7
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 210-214
    Reactivité
    • 173
    • 94
    • 82
    • 7
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Humain, Rat, Souris
    Hôte
    • 166
    • 4
    • 1
    • 1
    Lapin
    Clonalité
    • 160
    • 13
    Polyclonal
    Conjugué
    • 90
    • 10
    • 7
    • 7
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    Cet anticorp PAK1 est non-conjugé
    Application
    • 116
    • 66
    • 44
    • 39
    • 39
    • 34
    • 31
    • 14
    • 11
    • 10
    • 10
    • 6
    • 4
    • 3
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Specificité
    The antibody detects endogenous level of total PAK1protein.
    Purification
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific immunogen.
    Immunogène
    Peptide sequence around AA 210-214 (P-V-T-P-T) derived from Human PAK1. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
    Isotype
    IgG
    Top Product
    Discover our top product PAK1 Anticorps primaire
  • Indications d'application
    Western blotting: 1:500-1:1000
    Immunohistochemistry: 1:50-1:100
    Immunofluorescence: 1:100-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • Wang, Ma, Xu, Wang, Zhu, An, An, Wu, Tian: "Phosphorylation of histone H3 on Ser10 by auto-phosphorylated PAK1 is not essential for chromatin condensation and meiotic progression in porcine oocytes." dans: Journal of animal science and biotechnology, Vol. 4, Issue 1, pp. 13, (2013) (PubMed).

  • Antigène
    PAK1 (P21-Activated Kinase 1 (PAK1))
    Autre désignation
    PAK1 (PAK1 Produits)
    Synonymes
    anticorps X-PAK1, anticorps XPak1, anticorps pak, anticorps pak-1, anticorps pakalpha, anticorps PAKalpha, anticorps AW045634, anticorps PAK-1, anticorps Paka, anticorps p21 protein (Cdc42/Rac)-activated kinase 1 S homeolog, anticorps p21 (RAC1) activated kinase 1, anticorps p21 protein (Cdc42/Rac)-activated kinase 1, anticorps Serine/threonine-protein kinase pak-1, anticorps pak1.S, anticorps PAK1, anticorps Pak1, anticorps pak-1
    Sujet
    The activated kinase acts on a variety of targets. Likely to be the GTPase effector that links the Rho-related GTPases to the JNK MAP kinase pathway. Activated by CDC42 and RAC1. Involved in dissolution of stress fibers and reorganization of focal complexes. Involved in regulation of microtubule biogenesis through phosphorylation of TBCB. Activity is inhibited in cells undergoing apoptosis, potentially due to binding of CDC2L1 and CDC2L2.
    Poids moléculaire
    68 kDa
    NCBI Accession
    NP_001122
    UniProt
    Q13153
    Pathways
    Signalisation MAPK, Signalisation RTK, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Skeletal Muscle Fiber Development, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, Embryonic Body Morphogenesis
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