ABL1/2 anticorps (AA 391-395)

N° du produit ABIN363101

L’anticorps anti-ABL1/2 Polyclonal Lapin est utilisé pour la détection de ABL1/2 dans des échantillons de Humain et Souris. Il a été validé pour IHC et IF.

Aperçu rapide pour ABL1/2 anticorps (AA 391-395) (ABIN363101)

Antigène: ABL1/2 (ABL1/ABL2) (Abelson Murine Leukemia Viral Oncogene Homolog 1/2 (ABL1/ABL2))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ABL1/2 est non-conjugé

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-ABL1/2 anticorps

Épitope: AA 391-395

Specificité: The antibody detects endogenous levels of total ABL1/2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific immunogen. Specificity/Sensitivity ABL1/2 (Ab-393/429) Antibody detects endogenous levels of total ABL1/2 protein.

Immunogène: Peptide sequence around AA 391-395, 427-431 (D-T-Y-T-A) derived from ABL1, 2 Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.

Isotype: IgG

Information d'application

Indications d'application: Western blotting: 1:500-1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Détails sur ABL1/2

Antigène: ABL1/2 (ABL1/ABL2) (Abelson Murine Leukemia Viral Oncogene Homolog 1/2 (ABL1/ABL2))

Autre désignation: ABL1/2

Sujet: Regulates cytoskeleton remodeling during cell differentiation, cell division and cell adhesion. Localizes to dynamic actin structures, and phosphorylates CRK and CRKL, DOK1, and other proteins controlling cytoskeleton dynamics. Regulates DNA repair potentially by activating the proapoptotic pathway when the DNA damage is too severe to be repaired. Phosphorylates PSMA7 that leads to an inhibition of proteasomal activity and cell cycle transition blocks.

Poids moléculaire: 210 kDa

NCBI Accession: NP_001129, NP_005148

UniProt: P42684