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CD40 Ligand anticorps (FITC)

CD40LG Reactivité: Souris FACS Hôte: Hamster Monoclonal MR1 FITC
N° du produit ABIN370946
  • Antigène Voir toutes CD40 Ligand (CD40LG) Anticorps
    CD40 Ligand (CD40LG)
    Reactivité
    • 149
    • 82
    • 36
    • 9
    • 9
    • 7
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Souris
    Hôte
    • 87
    • 73
    • 25
    • 17
    • 11
    • 1
    Hamster
    Clonalité
    • 126
    • 82
    • 4
    Monoclonal
    Conjugué
    • 107
    • 22
    • 21
    • 15
    • 11
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CD40 Ligand est conjugé à/à la FITC
    Application
    • 121
    • 103
    • 57
    • 48
    • 39
    • 31
    • 21
    • 17
    • 15
    • 14
    • 13
    • 13
    • 7
    • 7
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Attributs du produit
    Synonyms: CD40 ligand, CD40-L, CD40LG, TNFSF5, TRAP, GP39, Tumor necrosis factor ligandsuperfamily member 5, TNF-related activation protein, T-cell antigen Gp39
    Immunogène
    Activated mouse Th1 clone D1. 6 (Ref. 1)
    Clone
    MR1
    Isotype
    IgG
    Top Product
    Discover our top product CD40LG Anticorps primaire
  • Indications d'application
    Flow Cytometry: < / 2 μg/10^6 cells. (Ref.1,5)
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    PBS containing 0.09 % Sodium Azide as preservative.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.
    Date de péremption
    12 months
  • Antigène
    CD40 Ligand (CD40LG)
    Autre désignation
    CD154 / CD40L (CD40LG Produits)
    Synonymes
    anticorps CD154, anticorps cd40l, anticorps CD40L, anticorps HIGM1, anticorps IGM, anticorps IMD3, anticorps T-BAM, anticorps TNFSF5, anticorps TRAP, anticorps gp39, anticorps hCD40L, anticorps CD40-L, anticorps Cd40l, anticorps Ly-62, anticorps Ly62, anticorps Tnfsf5, anticorps CD40 ligand, anticorps TNF superfamily member 5, anticorps CD40LG, anticorps cd40l, anticorps Cd40lg
    Sujet
    CD154, formerly known as CD40 ligand and gp39, is a type II integral membrane protein and a member of the tumor necrosis factor (TNF) family of ligands. (Ref.1-7) It is an important accessory molecule in T cell-B cell costimulatory interactions, and is expressed predominantly on activated CD4+ T lymphocytes. It is also present on the surface of activated Th0, Th1, and Th2 T cell clones. Its expression is transient and cyclosporinsensitive. (Ref.6) The MR1 monoclonal antibody binds to murine CD154 with high affinity, blocks binding to CD40, and blocks CD154 function. (Ref.1,5) Administration of this antibody to mice blocks the ability to mount primary and secondary immune responses to TD antigens, yet does not alter the immune response to TI antigens. (Ref.4)Synonyms: CD40 ligand, CD40-L, CD40LG, GP39, T-cell antigen Gp39, TNF-related activation protein, TNFSF5, TRAP, Tumor necrosis factor ligand superfamily member 5
    UniProt
    P27548
    Pathways
    Signalisation NF-kappaB, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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