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CTLA4 anticorps

CTLA4 Reactivité: Souris FACS, IP, Func Hôte: Hamster Monoclonal 1B8 unconjugated
N° du produit ABIN371058
  • Antigène Voir toutes CTLA4 Anticorps
    CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))
    Reactivité
    • 96
    • 67
    • 35
    • 5
    • 4
    Souris
    Hôte
    • 62
    • 52
    • 18
    • 12
    • 1
    • 1
    Hamster
    Clonalité
    • 89
    • 54
    • 2
    Monoclonal
    Conjugué
    • 68
    • 17
    • 13
    • 12
    • 8
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CTLA4 est non-conjugé
    Application
    • 87
    • 66
    • 52
    • 35
    • 19
    • 17
    • 14
    • 13
    • 10
    • 7
    • 7
    • 7
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunoprecipitation (IP), Functional Studies (Func)
    Specificité
    This Monoclonal antibody is specific to CD152/CTLA-4.
    Attributs du produit
    Synonyms: CTLA-4, Cytotoxic T-lymphocyte protein 4, Cytotoxic T-lymphocyte-associated antigen 4
    Purification
    Purified
    Clone
    1B8
    Isotype
    IgG
    Top Product
    Discover our top product CTLA4 Anticorps primaire
  • Indications d'application
    Flow Cytometry. (Ref.1,2)Immunoprecipitation. In vitro Functional Studies. (Ref.1,2)Enhancement of tumor immunity. (Ref.3)
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.
    Date de péremption
    12 months
  • Antigène
    CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))
    Autre désignation
    CD152 / CTLA4 (CTLA4 Produits)
    Synonymes
    anticorps CTLA-4, anticorps CTLA4, anticorps CD152, anticorps Cd152, anticorps Ctla-4, anticorps Ly-56, anticorps CD, anticorps CELIAC3, anticorps GRD4, anticorps GSE, anticorps IDDM12, anticorps sCTLA4, anticorps cytotoxic T-lymphocyte associated protein 4, anticorps cytotoxic T-lymphocyte-associated protein 4, anticorps CTLA4, anticorps Ctla4
    Sujet
    The lymphocyte surface antigen CD152, also known as CTLA-4, is related to the co-stimulatory molecule CD28, and both molecules share common B7 family counter-receptors. (Ref.1-4) However CD152 is thought to be a negative regulator of T cell activation (Ref.1-3) and may play a role in apoptotic control of T cells. CD152 exists as a 69 kDa homodimer (Ref.1), and is relatively conserved among Humans, Mice and Chickens. (Ref.2)Synonyms: CTLA-4, Cytotoxic T-lymphocyte protein 4, Cytotoxic T-lymphocyte-associated antigen 4
    ID gène
    100505288
    UniProt
    P09793
    Pathways
    Cancer Immune Checkpoints
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