Integrin beta 7 anticorps (Biotin)

N° du produit ABIN371133

Détail du produit anti-Integrin beta 7 anticorps (Biotin)

Antigène: Integrin beta 7 (ITGB7)

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp Integrin beta 7 est conjugé à/à la Biotin

Application: Flow Cytometry (FACS)

Specificité: This antibody is specific to mouse LPAM1 (Integrin alpha 4 beta 7). It recognises a conformational epitope on the heterodimer.

Attributs du produit: Synonyms: Integrin beta-P, M290 IEL antigen, ITGB7, LPAM-1, LPAM1, Lymphocyte Peyer PatchAdhesion Molecule

Immunogène: AKR/Cum mouse spontaneous T lymphoma cell line TK1. (Ref. 1)

Clone: DATK32

Isotype: IgG2a

Information d'application

Indications d'application: Flow Cytometry: < / = 1 μg/10^6 cells. (Ref.1-4)
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.09 % Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or in (aliquots) at -20 °C for longer. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur Integrin beta 7

Antigène: Integrin beta 7 (ITGB7)

Autre désignation: Integrin beta-7 (ITGB7 Produits)

Synonymes: anticorps Ly69, anticorps integrin beta 7, anticorps integrin subunit beta 7, anticorps integrin, beta 7, anticorps Itgb7, anticorps ITGB7

Sujet: The lymphocyte Peyer's patch adhesion molecule (LPAM-1), also known as Integrin alpha 4 beta 7 is a member of the integrin family of cell surface receptors. It is expressed primarily on mucosal lymphocytes, but is also present on NK cells and eosinophils. The alpha 4 beta 7 heterodimer mediates the binding of lymphocytes to its ligand, mucosal vascular addressin (MAdCAM1) on the high endothelial venules, thereby directing the homing of lymphocytes into Peyer's patches and intestinal lamina propria. (Ref.1-4) The Monoclonal antibody DATK32 has been shown to be useful for studies of the induction of homotypic cellular aggregation and the blockade of binding to cell adhesion molecules. (Ref.1)Synonyms: Adhesion Molecule, ITGB7, Integrin beta-P, LPAM-1, LPAM1, Lymphocyte Peyer Patch, M290 IEL antigen

ID gène: 16421

UniProt: P26011

Pathways: Integrin Complex