Retinoic Acid Receptor alpha anticorps (N-Term)

N° du produit ABIN371837

Détail du produit anti-Retinoic Acid Receptor alpha anticorps

Antigène: Retinoic Acid Receptor alpha (RARA) (Retinoic Acid Receptor, alpha (RARA))

Épitope: N-Term

Reactivité: Humain, Souris, Boeuf (Vache), Chien

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Retinoic Acid Receptor alpha est non-conjugé

Application: Western Blotting (WB)

Specificité: This antibody is specific for the ~48k RAR-alpha isotype.

Réactivité croisée (Details): Species reactivity (expected):Bovine, Canine (Dog) and Mouse.
Species reactivity (tested):Human.

Attributs du produit: Synonyms: NR1B1, Retinoic acid receptor alpha, Nuclear receptor subfamily 1 group B member 1

Purification: Prepared from Mouse Ascites by Ammonium Sulfate Precipitation followed by Affinity Chromatography on Protein G.

Immunogène: Peptide corresponding to amino acid residues from the N-terminal region of humanretinoic acid receptor, alpha-isotype.

Clone: 763

Isotype: IgG1

Information d'application

Indications d'application: Western Blot: 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.

Stock: -20 °C

Stockage commentaire: Store the antibody undiluted (in aliquots) at -20 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur Retinoic Acid Receptor alpha

Antigène: Retinoic Acid Receptor alpha (RARA) (Retinoic Acid Receptor, alpha (RARA))

Autre désignation: RAR-alpha / RARA (RARA Produits)

Synonymes: anticorps NR1B1, anticorps RAR, anticorps Nr1b1, anticorps RARalpha1, anticorps rar-alpha, anticorps etID309833.12, anticorps rara, anticorps rara2a, anticorps zRAR, anticorps zRAR-alpha, anticorps zgc:109797, anticorps nr1b1, anticorps RAR-ALPHA1, anticorps HS-RARa, anticorps fj66e06, anticorps rara2b, anticorps wu:fj66e06, anticorps retinoic acid receptor alpha, anticorps retinoic acid receptor, alpha, anticorps retinoic acid receptor, alpha a, anticorps retinoic acid receptor alpha L homeolog, anticorps retinoic acid receptor, alpha b, anticorps RARA, anticorps Rara, anticorps LOC100136372, anticorps raraa, anticorps rara.L, anticorps rara, anticorps rarab

Sujet: Retinoic acid (RA, active metabolite of vitamin A) plays a prominent role in regulating the transition of proliferating precursor cells (such as carcinoma cells and neuronal precursors) to postmitotic differentiated cells (Joshi et al., 2005). The retinoid X receptors (RXRs) family (RXR-alpha, beta and gamma), preferentially bind 9-cis-RA and regulate gene transcription by forming heterodimers with a second family of RA receptors. RAs have been suggested to potentially play a therapeutic role in cervical cancer (Abu et al., 2005). RAs are known to play key roles in neuronal development and an increasing body of evidence indicates that retinoid signaling may regulate synaptic plasticity and associated learning and memory behaviors (Lane and Bailey, 2005).Synonyms: NR1B1, Nuclear receptor subfamily 1 group B member 1, Retinoic acid receptor alpha

ID gène: 5914

UniProt: P10276

Pathways: Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, S100 Proteins