DLG4 anticorps (N-Term)

N° du produit ABIN372707

Détail du produit anti-DLG4 anticorps

Antigène: DLG4 (Discs, Large Homolog 4 (Drosophila) (DLG4))

Épitope: N-Term

Reactivité: Rat, Souris, Humain, Boeuf (Vache), Poisson zèbre (Danio rerio), Non-Human Primate

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DLG4 est non-conjugé

Application: Western Blotting (WB)

Specificité: This antibody recognizes the ~95k PSD95 protein.

Réactivité croisée (Details): Species reactivity (expected):Human, Bovine, Zebrafish and non-Human Primates.
Species reactivity (tested):Rat and Mouse.

Purification: Affinity Chromatography.

Immunogène: Peptide corresponding to amino acid residues from the N-terminal region of Rat PSD-95, conjugated to keyhole limpet hemocyanin (KLH).

Isotype: IgG

Information d'application

Indications d'application: Western blot: 1/1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody undiluted (in aliquots) at-20 °C.

Détails sur DLG4

Antigène: DLG4 (Discs, Large Homolog 4 (Drosophila) (DLG4))

Autre désignation: DLG4 / PSD95 (DLG4 Produits)

Synonymes: anticorps 11, anticorps CG1725, anticorps CG1730, anticorps CPD, anticorps DLG, anticorps DLG-A, anticorps Discs-large, anticorps Dlg, anticorps Dlg-A, anticorps Dlg1, anticorps DlgA, anticorps Dmel\\CG1725, anticorps Drodlg, anticorps PSD95, anticorps SAP97, anticorps anon-EST:Posey93, anticorps anon-WO03040301.258, anticorps anon-WO03040301.260, anticorps anon-WO03040301.268, anticorps d. lg.-1, anticorps dlg, anticorps dlg-1, anticorps dlg-A, anticorps dlgA, anticorps dlgS97, anticorps l(1)10Bf, anticorps l(1)G0276, anticorps l(1)G0342, anticorps l(1)G0456, anticorps l(1)G19, anticorps l(1)L11, anticorps l(1)bwn, anticorps l(1)d.lg-1, anticorps l(1)d.lg.-1, anticorps l(1)discs large, anticorps l(1)dlg, anticorps l(1)dlg-1, anticorps l(1)dlg1, anticorps l(1)l.pr.-2, anticorps l(1)lpr-2, anticorps misb, anticorps dlgh4, anticorps psd95, anticorps sap90, anticorps sap-90, anticorps LLGL1, anticorps Dlgh4, anticorps PSD-95, anticorps SAP90, anticorps SAP90A, anticorps Sap90, anticorps SAP-90, anticorps DLG4, anticorps discs large 1, anticorps discs, large homolog 4, anticorps discs large MAGUK scaffold protein 4, anticorps discs, large homolog 4b (Drosophila), anticorps discs, large homolog 4 (Drosophila), anticorps dlg1, anticorps dlg4, anticorps DLG4, anticorps dlg4b, anticorps Dlg4

Sujet: PSD95 is a very prominent component of the postsynaptic densities of synapses. It contains three PDZ domains which play key roles in its interactions with other proteins in the synapse. It has been proposed that these PDZ domains organize glutamate receptors and their associated signaling proteins and determine the size and strength of synapses (Kim and Sheng, 2004). Recent work suggests that interaction of the NMDAR with PSD-95 via these PDZ domains can be regulated by phosphorylation (Chung et al., 2004).Synonyms: DLGH4, Disks large homolog 4, PSD-95, Postsynaptic density protein 95, SAP-90, SAP90, Synapse-associated protein 90

ID gène: 29495

NCBI Accession: NP_062567

UniProt: P31016

Pathways: Regulation of Muscle Cell Differentiation, Synaptic Membrane, Skeletal Muscle Fiber Development, Asymmetric Protein Localization, Regulation of long-term Neuronal Synaptic Plasticity