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KIF5A anticorps (Center)

KIF5A Reactivité: Humain, Souris, Rat WB, IF, IHC (p), EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN372915
  • Antigène Voir toutes KIF5A Anticorps
    KIF5A (Kinesin Family Member 5A (KIF5A))
    Épitope
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Center
    Reactivité
    • 14
    • 12
    • 7
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 21
    • 1
    • 1
    Lapin
    Clonalité
    • 22
    • 1
    Polyclonal
    Conjugué
    • 18
    • 3
    • 2
    Cet anticorp KIF5A est non-conjugé
    Application
    • 22
    • 13
    • 8
    • 7
    • 7
    • 4
    • 4
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificité
    This antibody reacts to Kinesin Family Member 5A (KIF5A).
    Réactivité croisée (Details)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    Purification
    Immunoaffinity Chromatography.
    Immunogène
    Synthetic peptide - KLH conjugated corresponding to 20 amino acids from near the center of Human KIF5.
    Isotype
    IgG
    Top Product
    Discover our top product KIF5A Anticorps primaire
  • Indications d'application
    ELISA. Western blot: 0.5-1.0 μg/mL. Immunocytochemistry. Immunohistochemistry on Paraffin Sections: 5 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    PBS containing 0.02 % Sodium Azide as preservative.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Antigène
    KIF5A (Kinesin Family Member 5A (KIF5A))
    Autre désignation
    KIF5A (KIF5A Produits)
    Synonymes
    anticorps KIF5A, anticorps kif5a, anticorps si:ch211-166e11.4, anticorps wu:fj61a10, anticorps nkhc, anticorps my050, anticorps spg10, anticorps d12s1889, anticorps MGC122802, anticorps D12S1889, anticorps MY050, anticorps NKHC, anticorps SPG10, anticorps D10Bwg0738e, anticorps Khc, anticorps Kif5, anticorps Kns, anticorps mKIAA4086, anticorps kinesin family member 5A, anticorps kinesin family member 5A, a, anticorps KIF5A, anticorps kif5aa, anticorps kif5a, anticorps Kif5a
    Sujet
    Kinesins are microtubule-based motor proteins involved in the transport of organelles in eukaryotic cells. They typically consist of 2 identical, approximately 110- to 120-kD heavy chains and 2 identical, approximately 60- to 70-kD light chains. Kinesin heavy chain isoform 5A is a neuron-specific member of the kinesin 5 (Kif5) family, consisting of the heavy chains of conventional kinesins. Mutation in human homolog causes autosomal dominant spastic paraplegia 10. Kinesins are a superfamily of microtubule-associated motor proteins involved in a variety of cellular processes including membranous organelle transport and cell division. Kinesin has been found in a variety of organisms and cell types and is subject to spatial and temporal regulation. These proteins have a modular structure including a conserved motor domain of approximately 350 amino acids, which is responsible for microtubule binding and ATP hydrolysis. In addition to the motor domain, subfamily members share common domain organization, exhibit sequence similarity, motility properties, and cellular functions outside of the motor domain. There are currently three known Kinesin 5 family members denoted as A, B, and C. Kinesin 5A and kinesin 5C appear to be exclusively neuronal, whereas kinesin 5B appears to be ubiquitous in its expression.Synonyms: KIF5A, Kinesin heavy chain isoform 5A, Kinesin heavy chain neuron-specific 1, NKHC, NKHC1, Neuronal kinesin heavy chain
    Poids moléculaire
    110 kDa
    ID gène
    3798
    NCBI Accession
    NP_004975
    UniProt
    Q12840
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