NCF1 anticorps (C-Term)

N° du produit ABIN374079

Détail du produit anti-NCF1 anticorps

Antigène: NCF1 (Neutrophil Cytosol Factor 1 (NCF1))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Porc, Boeuf (Vache), Lapin

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp NCF1 est non-conjugé

Application: Western Blotting (WB)

Séquence: C-SESTKRKLAS AV

Specificité: This antibody detects NCF-1 at C-term.

Réactivité croisée (Details): Species reactivity (expected):Mouse, Rat, Rabbit, Pig, Cow.
Species reactivity (tested):Human.

Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide

Immunogène: Peptide from the C Terminus of the protein according to NP_000256.3. Genename: NCF1

Information d'application

Indications d'application: Peptide ELISA: Limit dilution 1: 20000. Western blot: 0.2-2 μg/mL. Approx 47 kDa band seen in U937 cell lysates.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur NCF1

Antigène: NCF1 (Neutrophil Cytosol Factor 1 (NCF1))

Autre désignation: NCF1 (NCF1 Produits)

Synonymes: anticorps NCF1A, anticorps NOXO2, anticorps SH3PXD1A, anticorps p47phox, anticorps Ncf-1, anticorps p47, anticorps neutrophil cytosolic factor 1, anticorps NCF1, anticorps Ncf1

Sujet: NCF1, along with NCF2 and a membrane bound cytochrome b558, is required for activation of the latent NADPH oxidase necessary for superoxide production. Defects in NCF1 are the cause of autosomal cytochrome-b-positive chronic granulomatous disease type 1 (CGD).Synonyms: 47 kDa autosomal chronic granulomatous disease protein, 47 kDa neutrophil oxidase factor, NCF-1, NCF-47K, NOXO2, Neutrophil NADPH oxidase factor 1, Neutrophil cytosol factor 1, Nox organizer 2, Nox-organizing protein 2, SH3 and PX domain-containing protein 1A, SH3PXD1A, p47-phox

ID gène: 653361

NCBI Accession: NP_000256

UniProt: P14598

Pathways: Signalisation PI3K-Akt