ADAM8
Reactivité: Humain
WB
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
Peptide ELISA: Limit dilution 1: 1000. Western blot: 1-3 μg/mL. Approx 90 kDa band seen in Human Brain lysate. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
anticorps CD156, anticorps MS2, anticorps CD156a, anticorps E430039A18Rik, anticorps adam8, anticorps reprolysin, anticorps si:zc217g15.7, anticorps zgc:64059, anticorps ADAM8, anticorps RGD1566394, anticorps ADAM metallopeptidase domain 8, anticorps a disintegrin and metalloproteinase domain 8, anticorps a disintegrin and metallopeptidase domain 8, anticorps ADAM metallopeptidase domain 8a, anticorps ADAM8, anticorps LOC100304737, anticorps Adam8, anticorps adam8a, anticorps adam8
Sujet
Members of ADAM family are cell surface proteins with a unique structure possessing both potential adhesion and protease domains. The extracellular region of ADAM8 shows significant amino acid sequence homology to hemorrhagic snake venom proteins, including the metalloprotease and disintegrin domains. The expression of ADAM8 is upregulated by retinoic acid and vitamin D3. The function of ADAM8 is still poorly understood. ADAM8 has been shown to stimulate osteoclasts, and to be produced by bone marrow cultures stimulated by vitamin-D. ADAM8 is involved in protein processing at the cell surface and is also thought to act as a leukocyte differentiation marker.Synonyms: Cell surface antigen MS2, Disintegrin and metalloproteinase domain-containing protein 8, MS2