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LAT anticorps (C-Term)

LAT Reactivité: Humain, Souris, Rat WB, EIA Hôte: Chèvre Polyclonal unconjugated
N° du produit ABIN374446
  • Antigène Voir toutes LAT Anticorps
    LAT (Linker For Activation of T Cells (LAT))
    Épitope
    • 19
    • 15
    • 15
    • 8
    • 8
    • 7
    • 7
    • 7
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 135
    • 59
    • 41
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 117
    • 18
    • 2
    • 1
    Chèvre
    Clonalité
    • 119
    • 19
    Polyclonal
    Conjugué
    • 66
    • 8
    • 8
    • 8
    • 6
    • 6
    • 6
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    Cet anticorp LAT est non-conjugé
    Application
    • 75
    • 41
    • 39
    • 39
    • 18
    • 12
    • 11
    • 9
    • 6
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Séquence
    C-GAPDYENLQE LN
    Specificité
    This antibody is expected to recognize isoform a (NP_055202.1), isoform b (NP_001014987.1 and NP_001014989.1) and isoform c (NP_001014988.1).
    Réactivité croisée (Details)
    Species reactivity (tested):Human, Mouse and Rat.
    Purification
    Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide.
    Immunogène
    Peptide from the C Terminus of the protein sequence according to NP_055202.1, NP_001014987.1, NP_001014989.1, NP_001014988.1
    Top Product
    Discover our top product LAT Anticorps primaire
  • Indications d'application
    Peptide ELISA: 1/2,000. Western Blot: 1-3 μg/mL. Detects a band of Approx 35 kDa in Human PBMC lysates(Predicted Molecular Weight: 35 kDa).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    -20 °C
    Stockage commentaire
    Store the antibody (in aliquots) at -20 °C.
  • Antigène
    LAT (Linker For Activation of T Cells (LAT))
    Autre désignation
    LAT (LAT Produits)
    Synonymes
    anticorps LAT, anticorps lat, anticorps LAT1, anticorps pp36, anticorps linker for activation of T-cells, anticorps linker for activation of T cells, anticorps LAT, anticorps lat, anticorps Lat
    Sujet
    Linker for activation of T cells (LAT) is an integral membrane protein (36 to 38 kD), which plays an important role in linking engagement of the TCR to the biochemical events of T cell activation. LAT antibody stains thymus and peripheral lymphoid tissues such as T cell areas in lymph nodes and spleen. LAT is expressed in T lymphocytes in interstitial spaces, platelets and megakaryocytes. LAT is not expressed in B cells, macrophages, plasma cells, monocytes, epithelial histiocytes and dendritic cells.Synonyms: 36 kDa Phospho-Tyrosine Adapter Protein, Linker For Activation of T-Cells Family Member 1, p36-38, pp36
    Poids moléculaire
    27.9kDa (NP_055202.1).
    ID gène
    27040
    NCBI Accession
    NP_001014987
    UniProt
    O43561
    Pathways
    TCR Signaling, Fc-epsilon Receptor Signaling Pathway
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