ANTXR1 anticorps (C-Term)

N° du produit ABIN374464

Détail du produit anti-ANTXR1 anticorps

Antigène: ANTXR1 (anthrax Toxin Receptor 1 (ANTXR1))

Épitope: C-Term

Reactivité: Humain

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp ANTXR1 est non-conjugé

Application: Western Blotting (WB)

Specificité: This antibody reacts to Anthrax toxin receptor 1.

Réactivité croisée (Details): Species reactivity (expected):Rat, Bovine, Canine.
Species reactivity (tested):Human.

Purification: Affinity chromatography

Immunogène: Peptide with sequence C-RAPPPSRPPPRPSV, from the C Terminus of the protein sequence

Information d'application

Indications d'application: Peptide ELISA: 1/64000. Western blot: 0.2 - 1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0,5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur ANTXR1

Antigène: ANTXR1 (anthrax Toxin Receptor 1 (ANTXR1))

Autre désignation: Anthrax Toxin Receptor 1 (ANTXR1 Produits)

Synonymes: anticorps ANTXR1, anticorps ATR, anticorps TEM8, anticorps 2310008J16Rik, anticorps 2810405N18Rik, anticorps Antrx1, anticorps Tem8, anticorps anthrax toxin receptor 1, anticorps ANTXR1, anticorps Antxr1

Sujet: TEM8 is a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. This protein has also been shown to be a docking protein or receptor for Bacillus anthracistoxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor(EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants have been described.Synonyms: ANTXR1, ATR, TEM8, Tumor endothelial marker 8

ID gène: 84168, 9606

UniProt: Q9H6X2