AKAP9 anticorps (C-Term)

N° du produit ABIN374523

Détail du produit anti-AKAP9 anticorps

Antigène: AKAP9 (A Kinase (PRKA) Anchor Protein (Yotiao) 9 (AKAP9))

Épitope: C-Term

Reactivité: Humain, Souris

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp AKAP9 est non-conjugé

Application: ELISA, Western Blotting (WB)

Specificité: This antibody reacts to AKAP9. This antibody is expected to recognise isoforms 2 and 3. The isoforms Yotiao, AKAP350B and AKAP350C are not recognized.

Réactivité croisée (Details): Species reactivity (expected):Mouse.
Species reactivity (tested):Human.

Purification: Affinity chromatography

Immunogène: Peptide with sequence C-SGSTTQFHAGMR, from the C Terminus of the protein sequence

Information d'application

Indications d'application: Peptide ELISA: 1/32000. Western Blot: 1 - 3 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0,5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur AKAP9

Antigène: AKAP9 (A Kinase (PRKA) Anchor Protein (Yotiao) 9 (AKAP9))

Autre désignation: AKAP9 (AKAP9 Produits)

Synonymes: anticorps AKAP-9, anticorps AKAP350, anticorps AKAP450, anticorps CG-NAP, anticorps HYPERION, anticorps LQT11, anticorps MU-RMS-40.16A, anticorps PPP1R45, anticorps PRKA9, anticorps YOTIAO, anticorps 5730481H23Rik, anticorps AW545847, anticorps C79026, anticorps mKIAA0803, anticorps Gisp, anticorps Yotiao, anticorps AKAP9, anticorps wu:fj02h02, anticorps prka9, anticorps yotiao, anticorps akap350, anticorps akap450, anticorps hyperion, anticorps AKAP120, anticorps A-kinase anchoring protein 9, anticorps A kinase (PRKA) anchor protein (yotiao) 9, anticorps A kinase (PRKA) anchor protein 9, anticorps A-kinase anchoring protein AKAP120, anticorps AKAP9, anticorps Akap9, anticorps akap9, anticorps CpipJ_CPIJ006715, anticorps CpipJ_CPIJ017436

Sujet: AKAP9 is a novel cytoskeletal protein specifically concentrated in the neuromuscular junction and neuronal synapes that interacts with specific splice variants of NMDA Receptor Subunit NR1 in a C1 exon cassette dependent manner. It has also been shown to physically attach the type I protein phosphatase (PP1) and the adenosine 3',5'-mono-phosphate (cAMP) dependent protein kinase (PKA) holoenzyme to NMDA receptors to regulate channel activity. NMDA receptors are involved with many important functions and dysfunctions of the nervous system, including synapse formation, synaptic plasticity, and excitotoxicity. AKAP9 research may lead to a clearer understanding of these neural processes by explaining how NMDA receptors are targeted to particular synapses, how this localization is regulated during development and synaptic activity, and how NMDA receptor activity is transduced into intracellular signals responsible for particular neuronal responses.Synonyms: A-kinase anchor protein 350 kDa, A-kinase anchor protein 450 kDa, A-kinase anchor protein 9, AKAP120-like protein, AKAP350, AKAP450, KIAA0803, Protein hyperion, Protein kinase A-anchoring protein 9, Protein yotiao, entrosome- and Golgi-localized PKN-associated protein

ID gène: 10142, 9606

UniProt: Q99996

Pathways: M Phase, SARS-CoV-2 Protein Interactome