Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

BID anticorps (C-Term)

BID Reactivité: Humain WB, EIA Hôte: Chèvre Polyclonal unconjugated
N° du produit ABIN374543
  • Antigène Voir toutes BID Anticorps
    BID (BH3 Interacting Domain Death Agonist (BID))
    Épitope
    • 18
    • 18
    • 16
    • 8
    • 8
    • 8
    • 7
    • 6
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 132
    • 67
    • 31
    • 3
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 140
    • 20
    • 3
    • 2
    Chèvre
    Clonalité
    • 131
    • 33
    Polyclonal
    Conjugué
    • 89
    • 17
    • 13
    • 7
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Cet anticorp BID est non-conjugé
    Application
    • 146
    • 63
    • 56
    • 39
    • 30
    • 28
    • 26
    • 19
    • 13
    • 13
    • 8
    • 7
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Séquence
    C-TYVRSLARNG MD
    Specificité
    This antibody reacts to BH3-interacting domain death agonist. It is expected to recognise all three reported isoforms (as represented by NP_932070.1, NP_001187.1, NP_932071.1)
    Réactivité croisée (Details)
    Species reactivity (tested):Human.
    Purification
    Affinity Chromatography
    Immunogène
    Peptide with sequence from the C Terminus of the protein sequence according to NP_932070.1, NP_001187.1, NP_932071.1. Genename: BID
    Top Product
    Discover our top product BID Anticorps primaire
  • Indications d'application
    Peptide ELISA: 1/8000. Western Blot: 0.1 - 0.3 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    Tris saline, pH ~7.3 containing 0.02 % Sodium Azide and 0.5 % BSA
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Antigène
    BID (BH3 Interacting Domain Death Agonist (BID))
    Autre désignation
    BID (BID Produits)
    Synonymes
    anticorps FP497, anticorps 2700049M22Rik, anticorps AI875481, anticorps AU022477, anticorps BID, anticorps bid, anticorps si:ch211-238n5.6, anticorps fp497, anticorps xbid, anticorps DKFZp469E066, anticorps BH3 interacting domain death agonist, anticorps BH3 interacting domain death agonist S homeolog, anticorps BID, anticorps Bid, anticorps bida, anticorps bid.S, anticorps bid
    Sujet
    Bid, a BH3 domain containing proapoptotic Bcl2 family member, is localized in the cytosolic fraction of cells as an inactive precursor. Its active form is generated upon proteolytic cleavage by caspase 8 in the Fas signaling pathway. Cleaved Bid translocates to mitochondria and releases its potent proapoptotic activity, which in turn induces cytochrome c release and mitochondrial damage. The cytochrome c releasing activity of Bid was antagonized by Bcl2. Mutation in the SH3 domain can diminish the cytochrome c releasing activity. In animal model studies, Bid deficient mice are found resistant to the lethal effects of death factor signals relayed through Fas.Synonyms: BH3-interacting domain death agonist, p22 BID
    Poids moléculaire
    26.8kDa (NP_932070.1) and 22.0kDa (NP_001187.1).
    ID gène
    637, 9606
    UniProt
    P55957
    Pathways
    Apoptose, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
Vous êtes ici:
Support technique