GATA1 anticorps (Internal Region)

N° du produit ABIN374593

Détail du produit anti-GATA1 anticorps

Antigène: GATA1 (GATA Binding Protein 1 (Globin Transcription Factor 1) (GATA1))

Épitope: Internal Region

Reactivité: Humain

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp GATA1 est non-conjugé

Application: Western Blotting (WB)

Specificité: This antibody reacts to GATA1.

Réactivité croisée (Details): Species reactivity (expected):Mouse, Rat, Canine, Bovine.
Species reactivity (tested):Human.

Purification: Affinity chromatography

Immunogène: Peptide with sequence C-DAEAYRHSPVFQ, from the internal region of the protein sequence

Information d'application

Indications d'application: Peptide ELISA: 1/16000. Western Blot: 0.3 - 1.0 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0,5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur GATA1

Antigène: GATA1 (GATA Binding Protein 1 (Globin Transcription Factor 1) (GATA1))

Autre désignation: GATA1 (GATA1 Produits)

Synonymes: anticorps ERYF1, anticorps GATA-1, anticorps GF-1, anticorps GF1, anticorps NF-E1, anticorps NFE1, anticorps XLANP, anticorps XLTDA, anticorps XLTT, anticorps Gata-1, anticorps Gf-1, anticorps eryf1, anticorps Eryf1, anticorps GATA1, anticorps gata-1, anticorps Gata1, anticorps si:dkeyp-77f7.5, anticorps gata1, anticorps gata1a-A, anticorps xGATA-1, anticorps xgata1, anticorps XGATA-1B, anticorps gata1b-A, anticorps gta1, anticorps zg1, anticorps NF-E1a, anticorps GATA binding protein 1, anticorps GATA binding protein 1 (globin transcription factor 1), anticorps amidase, anticorps aspartyl/glutamyl-tRNA amidotransferase subunit A, anticorps putative amidase, anticorps GatA1, anticorps glutamyl-tRNA amidotransferase subunit A, anticorps hematopietic transcription factor GATA-1, anticorps GATA binding protein 1b, anticorps GATA binding protein 1 L homeolog, anticorps GATA binding protein 1 S homeolog, anticorps GATA binding protein 1a, anticorps erythroid transcription factor, anticorps GATA1, anticorps Gata1, anticorps gatA1, anticorps gata-1, anticorps gata1b, anticorps gata1.L, anticorps gata1.S, anticorps gata1a, anticorps LOC108348091

Sujet: GATA1 (Globin transcription factor 1) is a Cys2/Cys2 zinc finger DNA binding protein that is expressed primarily in erythroid, megakaryocytic, mast cells and eosinophilic cells. It belongs to the GATA family of transcription factors. GATA1 is a transcriptional activator which probably serves as a general switch factor for erythroid development. It binds to DNA sites with the consensus sequence [AT]GATA[AG] within regulatory regions of globin genes and of other genes expressed in erythroid cells. The protein also plays an important role in erythroid development by regulating the switch from fetal hemoglobin production to adult hemoglobin. Mutations in this gene have been associated with X-linked dyserythropoietic anemia and thrombocytopenia. Acquired somatic mutations in GATA1 occur in virtually all children with Down's Syndrome, congenital transient myeloproliferative syndrome (TMD) and acute megakaryocytic leukemia.Synonyms: ERYF1, Eryf1, Erythroid transcription factor, GATA-1, GATA-binding factor 1, GF-1, GF1, NF-E1 DNA-binding protein

ID gène: 2623

NCBI Accession: NP_002040

UniProt: P15976

Pathways: Cellular Response to Molecule of Bacterial Origin