DCP1A anticorps (C-Term)

N° du produit ABIN374653

Détail du produit anti-DCP1A anticorps

Antigène: DCP1A (DCP1 Decapping Enzyme Homolog A (S. Cerevisiae) (DCP1A))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp DCP1A est non-conjugé

Application: Western Blotting (WB)

Specificité: This antibody reacts to DCP1A.

Réactivité croisée (Details): Species reactivity (expected):Mouse, Rat.
Species reactivity (tested):Human.

Purification: Affinity chromatography

Immunogène: Peptide with sequence C-QVLTKNKDNHN, from the C Terminus of the protein sequence

Information d'application

Indications d'application: Peptide ELISA: 1/4000. Western Blot: 1 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur DCP1A

Antigène: DCP1A (DCP1 Decapping Enzyme Homolog A (S. Cerevisiae) (DCP1A))

Autre désignation: DCP1A (DCP1A Produits)

Synonymes: anticorps DCP1A, anticorps 1110066A22Rik, anticorps 4930568L04Rik, anticorps AU019772, anticorps D14Ertd817e, anticorps Mitc1, anticorps SMIF, anticorps RGD1561298, anticorps mitc1, anticorps HSA275986, anticorps Nbla00360, anticorps SMAD4IP1, anticorps smad4ip1, anticorps smif, anticorps decapping mRNA 1A, anticorps decapping mRNA 1A L homeolog, anticorps DCP1A, anticorps Dcp1a, anticorps dcp1a, anticorps dcp1a.L

Sujet: Dcp1a is necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. Removes the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP. Contributes to the transactivation of target genes after stimulation by TGFB1. Dcp1a binds DCP1B, DCP2, RENT1 and SMAD4 and forms part of a cytoplasmic complex containing proteins involved in mRNA decay, including XRN1 and LSM1.Synonyms: SMIF, Smad4-interacting transcriptional co-activator, Transcription factor SMIF, mRNA-decapping enzyme 1A

ID gène: 55802, 9606

UniProt: Q9NPI6