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CTNNA1 anticorps (Internal Region)

CTNNA1 Reactivité: Humain, Souris, Rat, Chien WB Hôte: Chèvre Polyclonal unconjugated
N° du produit ABIN374681
  • Antigène Voir toutes CTNNA1 Anticorps
    CTNNA1 (Catenin (Cadherin-Associated Protein), alpha 1, 102kDa (CTNNA1))
    Épitope
    • 12
    • 7
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivité
    • 83
    • 50
    • 34
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    Humain, Souris, Rat, Chien
    Hôte
    • 65
    • 18
    • 1
    Chèvre
    Clonalité
    • 55
    • 29
    Polyclonal
    Conjugué
    • 49
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CTNNA1 est non-conjugé
    Application
    • 48
    • 30
    • 21
    • 19
    • 17
    • 15
    • 12
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Specificité
    This antibody reacts to Catenin alpha-1 / CTNNA1.
    Réactivité croisée (Details)
    Species reactivity (expected):Mouse, Rat, Canine.
    Species reactivity (tested):Human.
    Purification
    Affinity chromatography
    Immunogène
    Peptide with sequence C-KREKQDETQTKIK, from the internal region of the protein sequence
    Top Product
    Discover our top product CTNNA1 Anticorps primaire
  • Indications d'application
    Peptide ELISA: 1/32000. Western Blot: 1 - 3 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Antigène
    CTNNA1 (Catenin (Cadherin-Associated Protein), alpha 1, 102kDa (CTNNA1))
    Autre désignation
    Catenin alpha-1 / CTNNA1 (CTNNA1 Produits)
    Synonymes
    anticorps CAP102, anticorps 2010010M04Rik, anticorps AA517462, anticorps AI988031, anticorps Catna1, anticorps CG17947, anticorps CT39986, anticorps Dalpha-Cat, anticorps Dalpha-cat, anticorps DalphaC, anticorps Dalphacat, anticorps Dmcatp, anticorps Dmel\\CG17947, anticorps a-Cat, anticorps a-cat, anticorps alpha-CAT, anticorps alpha-cat, anticorps alpha-catenin, anticorps alpha-ctn, anticorps alphaCAT, anticorps alphaCat, anticorps alphacat, anticorps Alpha-Cat, anticorps dgri_GLEANR_3829, anticorps DgriGH19548, anticorps GH19548, anticorps ctnna, anticorps cap102, anticorps catna1, anticorps ctnna1, anticorps catenin alpha 1, anticorps catenin (cadherin associated protein), alpha 1, anticorps alpha Catenin, anticorps catenin alpha-1, anticorps catenin (cadherin-associated protein), alpha 1, anticorps catenin alpha 1 S homeolog, anticorps CTNNA1, anticorps Ctnna1, anticorps alpha-Cat, anticorps Dgri\alpha-Cat, anticorps Tsp_10127, anticorps ctnna1, anticorps ctnna1.S
    Sujet
    The distinct peripheral cytosolic proteins, alpha, beta and gamma-catenin (102, 94 and 86 kDa) found in many tissues bind to the conserved cytoplasmic tail domain of the cell-adhesion cadherins. Catenins link E-cadherin to other integral membrane or cytoplasmic proteins and are modulated by Wnt-1 proto-oncogene. They are good candidates for mediating transduction of cell-cell contact positional signals to the cell interior. Absence of alpha-catenin is found in certain tumor cell lines and reduced levels in certain human carcinomas. Beta-catenin binds directly to the cytoplasmic tail of E-cadherin. It binds to the N-terminus of alpha-catenin and interacts with the protein product of the tumor suppressor gene APC. This interaction involves a 15-aa repeat in the APC. Beta-catenin cell levels seem to be controlled by APC. The central core region of beta-catenin is involved in mediation of cadherin-catenin complex interaction with EGFR.Synonyms: Alpha Catenin, Alpha E-catenin, Cadherin-associated protein, NY-REN-13 antigen
    ID gène
    1495, 9606
    UniProt
    P35221
    Pathways
    Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Maintenance of Protein Location
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