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ERP29 anticorps (C-Term)

ERP29 Reactivité: Humain, Rat, Souris, Chien, Boeuf (Vache), Porc WB Hôte: Chèvre Polyclonal unconjugated
N° du produit ABIN375036
  • Antigène Voir toutes ERP29 Anticorps
    ERP29 (Endoplasmic Reticulum Protein 29 (ERP29))
    Épitope
    • 15
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 49
    • 47
    • 33
    • 16
    • 13
    • 13
    • 12
    • 4
    • 2
    • 1
    • 1
    • 1
    Humain, Rat, Souris, Chien, Boeuf (Vache), Porc
    Hôte
    • 60
    • 4
    • 1
    Chèvre
    Clonalité
    • 52
    • 11
    Polyclonal
    Conjugué
    • 23
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ERP29 est non-conjugé
    Application
    • 41
    • 19
    • 14
    • 14
    • 14
    • 10
    • 5
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB)
    Specificité
    This antibody reacts to ERP29.
    Réactivité croisée (Details)
    Species reactivity (expected):Mouse, Rat, Canine, Bovine, Porcine.
    Species reactivity (tested):Human.
    Purification
    Affinity chromatography
    Immunogène
    Peptide with sequence C-EKNKMSDGKKEELQ, from the C-Terminus of the protein sequence
    Top Product
    Discover our top product ERP29 Anticorps primaire
  • Indications d'application
    Peptide ELISA: 1/2000. Western Blot: 0.1 - 0.3 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    0,5 mg/mL
    Buffer
    Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Antigène
    ERP29 (Endoplasmic Reticulum Protein 29 (ERP29))
    Autre désignation
    ERP29 (ERP29 Produits)
    Synonymes
    anticorps C12orf8, anticorps ERp28, anticorps ERp31, anticorps PDI-DB, anticorps PDIA9, anticorps 1200015M03Rik, anticorps 2810446M09Rik, anticorps AW209030, anticorps Erp28, anticorps Erp31, anticorps PDI-Db, anticorps endoplasmic reticulum protein 29, anticorps ERP29, anticorps Erp29
    Sujet
    Proper protein folding and post-translational modifications are essential for secretory protein export out of the endoplasmic reticulum. This task is accomplished by chaperone proteins such as protein disulfide isomerase (PDI), GRP94, and BiP. A recently characterized protein, designated ERp29, is closely related to these chaperone proteins and appears to be upregulated during ER stress conditions. ERp29 is a soluble 259-residue protein that is localized to the lumen of the endoplasmic reticulum in all mammalian cells. Research has shown that there are two primary domains within ERp29. The first is the C-terminal region that is a novel, all helical, fold that is most likely involved with ERp29 retention to the ER. The second is the N-terminal region that resembles that of PDI's thioredoxin module. The protein shows sequence similarity to the protein disulfide isomerase family. However, it lacks the thioredoxin motif characteristic of this family, suggesting that this protein does not function as a disulfide isomerase. The protein dimerizes and is thought to play a role in the processing of secretory proteins within the ER.Synonyms: C12orf8, ERp28, ERp31, Endoplasmic reticulum protein ERp29
    ID gène
    10961
    NCBI Accession
    NP_006808
    UniProt
    P30040
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