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KCNJ1 anticorps (Internal Region)

KCNJ1 Reactivité: Humain, Rat, Souris WB Hôte: Chèvre Polyclonal unconjugated
N° du produit ABIN375086
  • Antigène Voir toutes KCNJ1 Anticorps
    KCNJ1 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 1 (KCNJ1))
    Épitope
    • 19
    • 16
    • 8
    • 8
    • 6
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivité
    • 55
    • 25
    • 9
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain, Rat, Souris
    Hôte
    • 70
    • 1
    • 1
    Chèvre
    Clonalité
    • 72
    Polyclonal
    Conjugué
    • 22
    • 9
    • 7
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp KCNJ1 est non-conjugé
    Application
    • 38
    • 26
    • 26
    • 26
    • 14
    • 10
    • 9
    • 8
    • 6
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    C-DQININFVVD AGNEN
    Specificité
    This antibody is expected to recognize reported isoforms (NP_722449.2 and NP_000211) of KCNJ1.
    Réactivité croisée (Details)
    Species reactivity (expected):Mouse, Rat.
    Species reactivity (tested):Human.
    Purification
    Affinity Chromatography.
    Immunogène
    Peptide with sequence from the internal region of the protein sequence according to NP_000211.1, NP_722448.1. Genename: KCNJ1
    Top Product
    Discover our top product KCNJ1 Anticorps primaire
  • Indications d'application
    Peptide ELISA: 1/8000. Western Blot: 1 - 3 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    Tris saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Antigène
    KCNJ1 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 1 (KCNJ1))
    Autre désignation
    KCNJ1 (KCNJ1 Produits)
    Synonymes
    anticorps KIR1.1, anticorps ROMK, anticorps ROMK1, anticorps kir1.1, anticorps romk1, anticorps Kcnj, anticorps Kir1.1, anticorps Romk2, anticorps kcnj1, anticorps wu:fl37c05, anticorps zgc:63534, anticorps potassium voltage-gated channel subfamily J member 1, anticorps potassium voltage-gated channel subfamily J member 1 L homeolog, anticorps potassium inwardly-rectifying channel, subfamily J, member 1, anticorps potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 1, anticorps KCNJ1, anticorps kcnj1.L, anticorps kcnj1, anticorps Kcnj1, anticorps kcnj1a.1
    Sujet
    Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. KCNJ1 is an integral membrane protein and inward rectifier type potassium channel. It is activated by internal ATP and probably plays an important role in potassium homeostasis. The KCNJ1 channel is blocked by external barium. WNK1 has been shown to inhibit KCNJ1 by enhancing its endocytosis. Mutations in this gene have been associated with antenatal Bartter syndrome, which is characterized by salt wasting, hypokalemic alkalosis, hypercalciuria, and low blood pressure.Synonyms: ATP-regulated potassium channel ROM-K, ATP-sensitive inward rectifier potassium channel 1, KCNJ1, Kir1.1, Potassium channel, ROMK1, inwardly rectifying subfamily J member 1
    ID gène
    3758
    NCBI Accession
    NP_000211
    UniProt
    P48048
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