IDE anticorps (Internal Region)
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- Antigène Voir toutes IDE Anticorps
- IDE (Insulin-Degrading Enzyme (IDE))
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Épitope
- Internal Region
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Reactivité
- Humain, Chien
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Hôte
- Chèvre
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp IDE est non-conjugé
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Application
- Western Blotting (WB)
- Specificité
- This antibody reacts to Insulysin / Insulinase.
- Réactivité croisée (Details)
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Species reactivity (expected):Canine.
Species reactivity (tested):Human. - Purification
- Affinity chromatography
- Immunogène
- Peptide with sequence C-QQYNFDRDNTE, from the internal region of the protein sequence
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- Indications d'application
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Peptide ELISA: 1/32000. Western Blot: 0.1 - 0.3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 0,5 mg/mL
- Buffer
- Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Antigène
- IDE (Insulin-Degrading Enzyme (IDE))
- Autre désignation
- Insulin-Degrading Enzyme (IDE Produits)
- Synonymes
- anticorps zgc:162603, anticorps IDE, anticorps 1300012G03Rik, anticorps 4833415K22Rik, anticorps AA675336, anticorps AI507533, anticorps INSDEGM, anticorps INSULYSIN, anticorps insulin degrading enzyme, anticorps insulin-degrading enzyme, anticorps metallopeptidase, anticorps IDE, anticorps ide, anticorps LOC591315, anticorps CC1G_01115, anticorps Bm1_26615, anticorps PTRG_10875, anticorps SJAG_01430, anticorps EBI_21700, anticorps VDBG_06702, anticorps LOAG_08082, anticorps PGTG_04982, anticorps Tsp_00424, anticorps Ide
- Sujet
- Insulin degrading enzyme (IDE) has a preferential affinity for insulin such that the presence of insulin will inhibit IDE mediated degradation of other substrates. IDE degrades a variety of other peptides including atrial natriuretic peptide and amylin. IDE catabolizes A beta and has been implicated as a candidate enzyme responsible for the degradation and clearance of A beta in the brain. IDE has also been shown to degrade the APP intracellular domain (AICD), a product of gamma secretase cleaved APP that may function in nuclear signaling.Synonyms: Abeta-degrading protease, EC=3.4.24.56, IDE, Insulin protease, Insulinase, Insulysin
- ID gène
- 3416, 9606
- UniProt
- P14735
- Pathways
- SARS-CoV-2 Protein Interactome
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