Biglycan anticorps (C-Term)
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- Antigène Voir toutes Biglycan (BGN) Anticorps
- Biglycan (BGN)
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Épitope
- C-Term
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Reactivité
- Humain, Rat, Souris, Chien
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Hôte
- Chèvre
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Biglycan est non-conjugé
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Application
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Séquence
- C-DRLAIQFGNY KK
- Specificité
- This antibody recognizes Biglycan Preproprotein.
- Réactivité croisée (Details)
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Species reactivity (expected):Mouse, Canine.
Species reactivity (tested):Human, Rat. - Purification
- Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide
- Immunogène
- Synthetic peptide from the C-Terminus of Human Biglycan (NP_001702.1) Genename: BGN
- Top Product
- Discover our top product BGN Anticorps primaire
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- Indications d'application
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Peptide ELISA: 1/8000. Western Blot: 0.1 - 0.3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Antigène
- Biglycan (BGN)
- Autre désignation
- Biglycan (BGN Produits)
- Synonymes
- anticorps DSPG1, anticorps PG-S1, anticorps PGI, anticorps SLRR1A, anticorps BG, anticorps BSPG1, anticorps bgn, anticorps zgc:91989, anticorps dspg1, anticorps pg-s1, anticorps slrr1a, anticorps xbgn, anticorps BGN, anticorps zgc:77123, anticorps DKFZp468I2427, anticorps biglycan, anticorps biglycan L homeolog, anticorps biglycan a, anticorps biglycan S homeolog, anticorps biglycan b, anticorps BGN, anticorps Bgn, anticorps bgn.L, anticorps bgna, anticorps bgn.S, anticorps bgn, anticorps bgnb
- Sujet
- Biglycan is an extracellular matrix proteoglycan that is closely related in structure to decorin and fibromodulin. Biglycan and decorin are thought to be the result of a gene duplication. Biglycan is expressed in secondary myotubes during fetal muscle formation. In adult muscle it is located in the endomysium and neuromuscular junctions, where it connects to the dystrophin-associated proteins through binding to a-dystroglycan. In developing newborn mice biglycan expression is initially high and then decreases during skeletal muscle differentiation and maturation. Biglycan may also have a role in the fibrotic process since it is overexpressed in atherosclerotic lesions and has been shown to cause an increase in thymidine incorporation and migration of vascular smooth muscle cells.Synonyms: BGN, Bone/cartilage proteoglycan I, PG-S1, PGS1, SLRR1A, Small Leucine-rich Protein 1A
- Poids moléculaire
- 41.7 kDa (Human NP_001702.1 and Rat NP_058783.1)
- ID gène
- 633
- NCBI Accession
- NP_001702
- UniProt
- P21810
- Pathways
- Glycosaminoglycan Metabolic Process
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