NCOR1 anticorps (N-Term)

N° du produit ABIN387976

Détail du produit anti-NCOR1 anticorps

Antigène: NCOR1 (Nuclear Receptor Co-Repressor 1 (NCOR1))

Épitope: AA 16-47, N-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NCOR1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This NCOR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 16-47 amino acids from the N-terminal region of human NCOR1.

Clone: RB2594

Isotype: Ig Fraction

Information d'application

Indications d'application: IF: 1:10~50. WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur NCOR1

Antigène: NCOR1 (Nuclear Receptor Co-Repressor 1 (NCOR1))

Autre désignation: NCOR1 (NCOR1 Produits)

Synonymes: anticorps ncor, anticorps zgc:56355, anticorps 5730405M06Rik, anticorps A230020K14Rik, anticorps N-CoR, anticorps RIP13, anticorps Rxrip13, anticorps mKIAA1047, anticorps N-CoR1, anticorps TRAC1, anticorps hN-CoR, anticorps nuclear receptor corepressor 1, anticorps nuclear receptor co-repressor 1, anticorps nuclear receptor corepressor 1 pseudogene, anticorps nuclear receptor corepressor 1 S homeolog, anticorps ncor1, anticorps NCOR1, anticorps CpipJ_CPIJ002507, anticorps LOC100343278, anticorps Ncor1, anticorps ncor1.S

Sujet: NCOR1 mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. The gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. An alternatively spliced transcript variant has been described, but its full length sequence has not been determined.

Poids moléculaire: 270210

ID gène: 9611

NCBI Accession: NP_001177367, NP_001177369, NP_006302

UniProt: O75376

Pathways: Nuclear Hormone Receptor Binding, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process