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PIAS4 anticorps (C-Term)

PIAS4 Reactivité: Humain WB, IHC (p) Hôte: Lapin Polyclonal RB00682 unconjugated
N° du produit ABIN388062
  • Antigène Voir toutes PIAS4 Anticorps
    PIAS4 (Protein Inhibitor of Activated STAT, 4 (PIAS4))
    Épitope
    • 19
    • 12
    • 8
    • 8
    • 6
    • 5
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 471-499, C-Term
    Reactivité
    • 65
    • 33
    • 9
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 69
    • 2
    Lapin
    Clonalité
    • 70
    • 1
    Polyclonal
    Conjugué
    • 31
    • 8
    • 7
    • 7
    • 6
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp PIAS4 est non-conjugé
    Application
    • 60
    • 44
    • 30
    • 8
    • 5
    • 4
    • 3
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogène
    This PIASy1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 471-499 amino acids from the C-terminal region of human PIASy1.
    Clone
    RB00682
    Isotype
    Ig Fraction
    Top Product
    Discover our top product PIAS4 Anticorps primaire
  • Indications d'application
    WB: 1:1000. IHC-P: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Date de péremption
    6 months
  • Antigène
    PIAS4 (Protein Inhibitor of Activated STAT, 4 (PIAS4))
    Autre désignation
    PIASy1 (PIAS4 Produits)
    Synonymes
    anticorps PIASY, anticorps Piasg, anticorps ZMIZ6, anticorps pias4, anticorps piasy, anticorps wu:fc54c11, anticorps wu:fi18c10, anticorps wu:fi20e09, anticorps wu:fk93f11, anticorps zgc:66410, anticorps piasg, anticorps zmiz6, anticorps LOC100219439, anticorps Pias-gamma, anticorps pias4l, anticorps wu:fi26h11, anticorps zgc:63923, anticorps protein inhibitor of activated STAT 4, anticorps protein inhibitor of activated STAT, 4, anticorps protein inhibitor of activated STAT, 4a, anticorps protein inhibitor of activated STAT 4 L homeolog, anticorps protein inhibitor of activated STAT, 4b, anticorps PIAS4, anticorps Pias4, anticorps pias4a, anticorps pias4.L, anticorps pias4, anticorps pias4b
    Sujet
    PIASy1 functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. This protein plays a crucial role in transcriptional coregulation of various cellular pathways, including the STAT pathway, the p53 pathway, the wnt pathway and the steroid hormone signaling pathway. PIASy1 is involved in gene silencing, and promotes PARK7 sumoylation.
    Poids moléculaire
    56504
    ID gène
    51588
    NCBI Accession
    NP_056981
    UniProt
    Q8N2W9
    Pathways
    Signalistation JAK/STAT, Interferon-gamma Pathway, Positive Regulation of Response to DNA Damage Stimulus
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