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SUMO2 anticorps (C-Term)

SUMO2 Reactivité: Humain WB, IHC (p) Hôte: Lapin Polyclonal RB2761 unconjugated
N° du produit ABIN388085
  • Antigène Voir toutes SUMO2 Anticorps
    SUMO2 (Small Ubiquitin Related Modifier 2 (SUMO2))
    Épitope
    • 30
    • 10
    • 8
    • 7
    • 7
    • 7
    • 6
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 63-93, C-Term
    Reactivité
    • 110
    • 35
    • 29
    • 8
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 94
    • 24
    • 1
    Lapin
    Clonalité
    • 95
    • 25
    Polyclonal
    Conjugué
    • 60
    • 13
    • 10
    • 9
    • 8
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp SUMO2 est non-conjugé
    Application
    • 80
    • 70
    • 48
    • 22
    • 15
    • 9
    • 8
    • 5
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Homologie
    X, Zf, B, C, Ha, Pr, M, Pig, Rat
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogène
    This SUMO2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 63-93 amino acids from the C-terminal region of human SUMO2.
    Clone
    RB2761
    Isotype
    Ig Fraction
    Top Product
    Discover our top product SUMO2 Anticorps primaire
  • Indications d'application
    WB: 1:1000. WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Date de péremption
    6 months
  • Ito, Nakamura, Mori, Miki, Tanji, Wakabayashi: "Novel eosinophilic neuronal cytoplasmic inclusions in the external cuneate nucleus of humans." dans: Neuropathology : official journal of the Japanese Society of Neuropathology, Vol. 36, Issue 5, pp. 441-447, (2017) (PubMed).

    Mori, Tanji, Odagiri, Hattori, Hoshikawa, Kono, Yasui, Yokoi, Hasegawa, Kamitani, Yoshida, Wakabayashi: "Ubiquitin-related proteins in neuronal and glial intranuclear inclusions in intranuclear inclusion body disease." dans: Pathology international, Vol. 62, Issue 6, pp. 407-11, (2012) (PubMed).

    Mori, Miki, Tanji, Ogura, Yagihashi, Jensen, Wakabayashi: "Incipient intranuclear inclusion body disease in a 78-year-old woman." dans: Neuropathology : official journal of the Japanese Society of Neuropathology, Vol. 31, Issue 2, pp. 188-93, (2011) (PubMed).

    Janer, Werner, Takahashi-Fujigasaki, Daret, Fujigasaki, Takada, Duyckaerts, Brice, Dejean, Sittler: "SUMOylation attenuates the aggregation propensity and cellular toxicity of the polyglutamine expanded ataxin-7." dans: Human molecular genetics, Vol. 19, Issue 1, pp. 181-95, (2009) (PubMed).

    Zhang, Sarge: "Sumoylation regulates lamin A function and is lost in lamin A mutants associated with familial cardiomyopathies." dans: The Journal of cell biology, Vol. 182, Issue 1, pp. 35-9, (2008) (PubMed).

  • Antigène
    SUMO2 (Small Ubiquitin Related Modifier 2 (SUMO2))
    Autre désignation
    SUMO2 (SUMO2 Produits)
    Synonymes
    anticorps HSMT3, anticorps SMT3B, anticorps SMT3H2, anticorps SUMO3, anticorps Smt3A, anticorps SMT3A, anticorps SMT3H1, anticorps SUMO-3, anticorps Smt3B, anticorps Smt3h2, anticorps sumo2, anticorps zgc:92241, anticorps SUMO2, anticorps SUMO-2, anticorps Smt3b, anticorps hsmt3, anticorps smt3b, anticorps smt3h2, anticorps sumo-2, anticorps PSMT3, anticorps ATSUMO2, anticorps MCO15.11, anticorps MCO15_11, anticorps SMALL UBIQUITIN-LIKE MODIFIER 2, anticorps SUM2, anticorps SUMO 2, anticorps small ubiquitin-like modifier 2, anticorps small ubiquitin-like modifier 2, anticorps small ubiquitin-like modifier 3, anticorps small ubiquitin-like modifier 2b, anticorps small ubiquitin-related modifier 2, anticorps small ubiquitin-like modifier 2 S homeolog, anticorps small ubiquitin-like modifier 2 L homeolog, anticorps SUMO2, anticorps SUMO3, anticorps Sumo2, anticorps sumo2b, anticorps LOC714892, anticorps sumo2.S, anticorps sumo2.L
    Sujet
    SUMO2 is a member of the SUMO (small ubiquitin-like modifier) protein family. This protein family functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. In vertebrates, three members of the SUMO family have been described, SUMO 1 and the functionally distinct homologues SUMO 2 and SUMO 3. SUMO modification sites present in the N terminal regions of SUMO 2 and SUMO 3 are utilized by SAE1/SAE2 (SUMO E1) and Ubc9 (SUMO E2) to form polymeric chains of SUMO 2 and SUMO 3 on protein substrates, a property not shared by SUMO 1.
    Poids moléculaire
    10871
    ID gène
    6613
    NCBI Accession
    NP_001005849, NP_008868
    UniProt
    P61956
    Pathways
    Methionine Biosynthetic Process
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