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ATG3 anticorps (N-Term)

ATG3 Reactivité: Humain WB Hôte: Lapin Polyclonal RB7456 unconjugated
N° du produit ABIN388486
  • Antigène Voir toutes ATG3 Anticorps
    ATG3 (ATG3 Autophagy Related 3 (ATG3))
    Épitope
    • 22
    • 15
    • 14
    • 11
    • 6
    • 6
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 2-31, N-Term
    Reactivité
    • 115
    • 42
    • 42
    • 7
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 117
    • 11
    • 3
    Lapin
    Clonalité
    • 110
    • 21
    Polyclonal
    Conjugué
    • 44
    • 12
    • 12
    • 10
    • 7
    • 7
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ATG3 est non-conjugé
    Application
    • 88
    • 55
    • 26
    • 26
    • 19
    • 18
    • 15
    • 14
    • 14
    • 8
    • 5
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Homologie
    B, M, Rat, X
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This ATG3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 2-31 amino acids from the N-terminal region of human ATG3.
    Clone
    RB7456
    Isotype
    Ig Fraction
    Top Product
    Discover our top product ATG3 Anticorps primaire
  • Indications d'application
    WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Date de péremption
    6 months
  • Antigène
    ATG3 (ATG3 Autophagy Related 3 (ATG3))
    Autre désignation
    ATG3 (ATG3 Produits)
    Synonymes
    anticorps atg3, anticorps im:6910145, anticorps wu:fb15g12, anticorps zgc:64156, anticorps APG3, anticorps APG3-LIKE, anticorps APG3L, anticorps PC3-96, anticorps 2610016C12Rik, anticorps Apg3l, anticorps Atg3l, anticorps PIG-1, anticorps Pig1, anticorps ATATG3, anticorps K11J9.1, anticorps K11J9_1, anticorps autophagy related 3, anticorps autophagy 3 (APG3), anticorps similar to S. cerevisiae ATG3 (YNR007C) part of ubiquitin-like system that mediates Atg8-phosphatidylethanolamine conjugation required for protein-vacuolar targeting and autophagy, anticorps atg3, anticorps ATG3, anticorps Atg3
    Sujet
    Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). APG3L is an E2-like conjugating enzyme facilitating covalent binding of APG8 (MAP1LC3) to phosphatidylethanolamine (PE). APG7 (an E1-like enzyme) facilitates this reaction by forming an E1-E2 complex with APG3. Formation of the PE conjugate is essential for autophagy.
    Poids moléculaire
    35864
    ID gène
    64422
    NCBI Accession
    NP_001265641, NP_071933
    UniProt
    Q9NT62
    Pathways
    Autophagy
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