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SLUG anticorps (N-Term)

Reactivité: Humain WB Hôte: Lapin Polyclonal RB15389 unconjugated
N° du produit ABIN388808
  • Antigène Tous les produits SLUG
    SLUG
    Épitope
    • 15
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-30, N-Term
    Reactivité
    • 26
    • 18
    • 15
    • 7
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 24
    • 2
    Lapin
    Clonalité
    • 23
    • 3
    Polyclonal
    Conjugué
    • 11
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp SLUG est non-conjugé
    Application
    • 25
    • 13
    • 13
    • 9
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Homologie
    B, M, Rat
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogène
    This SLUG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human SLUG.
    Clone
    RB15389
    Isotype
    Ig Fraction
  • Indications d'application
    WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C.
    Date de péremption
    6 months
  • Liang, Wang, Li, Yu, Zhang, Li: "miR-33a suppresses the nuclear translocation of ?-catenin to enhance gemcitabine sensitivity in human pancreatic cancer cells." dans: Tumour biology, (2015) (PubMed).

    Huo, Kao, Chuu: "Androgen receptor inhibits epithelial-mesenchymal transition, migration, and invasion of PC-3 prostate cancer cells." dans: Cancer letters, Vol. 369, Issue 1, pp. 103-11, (2015) (PubMed).

    Huang, Chen, Chang, Yuan, Jeng: "Hepatocyte growth factor activates Wnt pathway by transcriptional activation of LEF1 to facilitate tumor invasion." dans: Carcinogenesis, Vol. 33, Issue 6, pp. 1142-8, (2012) (PubMed).

    Collado, Thiede, Baker, Askew, Igbani, Corwin: "The postnatal accumulation of junctional E-cadherin is inversely correlated with the capacity for supporting cells to convert directly into sensory hair cells in mammalian balance organs." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 31, Issue 33, pp. 11855-66, (2011) (PubMed).

    Fu, Lv, Lin, Wu, Wang, Zhou, Zhang, Wang, Tsang, Zhu, Wang: "Ubiquitin ligase cullin 7 induces epithelial-mesenchymal transition in human choriocarcinoma cells." dans: The Journal of biological chemistry, Vol. 285, Issue 14, pp. 10870-9, (2010) (PubMed).

  • Antigène
    SLUG
    Abstract
    SLUG Produits
    Synonymes
    anticorps Slug, anticorps Slugh, anticorps Snail2, anticorps SLUG, anticorps SLUGH, anticorps SLUGH1, anticorps SNAIL2, anticorps WS2D, anticorps snail family zinc finger 2, anticorps snail family transcriptional repressor 2, anticorps Snai2, anticorps SNAI2
    Sujet
    SLUG is a member of the Snail family of C2H2-type zinc finger transcription factors. This protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in the gene encoding SLUG may be associated with sporadic cases of neural tube defects.
    Poids moléculaire
    29986
    NCBI Accession
    NP_003059
    UniProt
    O43623
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