LGR5 anticorps (N-Term)

N° du produit ABIN389215

Détail du produit anti-LGR5 anticorps

Antigène: LGR5 (Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5))

Épitope: AA 238-270, N-Term

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LGR5 est non-conjugé

Application: Western Blotting (WB)

Homologie: H

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This LGR5/GPR49 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 238-270 amino acids from the N-terminal region of human LGR5/GPR49.

Clone: RB14764

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-LGR5 (ABIN389215)

Usui, Sakurai, Enjoji, Kawasaki, Umata, Ohama, Fujiwara, Yabe, Tsuji, Yamawaki, Hazama, Takenouchi, Nakajima, Tsunedomi, Suzuki, Nagano, Sato: "Establishment of a Novel Model for Anticancer Drug Resistance in Three-Dimensional Primary Culture of Tumor Microenvironment." dans: Stem cells international, Vol. 2016, pp. 7053872, (2017) (PubMed).

Fender, Nutter, Bertrand, Sigounas: "Notch-1 Promotes Stemness and Epithelial to Mesenchymal Transition in Colorectal Cancer." dans: Journal of cellular biochemistry, (2015) (PubMed).

Jardé, Kass, Staples, Lescesen, Carne, Oliva, McMurrick, Abud: "ERBB3 Positively Correlates with Intestinal Stem Cell Markers but Marks a Distinct Non Proliferative Cell Population in Colorectal Cancer." dans: PLoS ONE, Vol. 10, Issue 9, pp. e0138336, (2015) (PubMed).

Kanwar, Yu, Nautiyal, Patel, Majumdar: "The Wnt/beta-catenin pathway regulates growth and maintenance of colonospheres." dans: Molecular cancer, Vol. 9, pp. 212, (2010) (PubMed).

Détails sur LGR5

Antigène: LGR5 (Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5))

Autre désignation: LGR5/GPR49 (LGR5 Produits)

Synonymes: anticorps lgr5-a, anticorps lgr5a, anticorps FEX, anticorps Gpr49, anticorps GPR49, anticorps GPR67, anticorps GRP49, anticorps HG38, anticorps leucine-rich repeat containing G protein-coupled receptor 5 L homeolog, anticorps leucine rich repeat containing G protein coupled receptor 5, anticorps leucine rich repeat containing G protein-coupled receptor 5, anticorps lgr5.L, anticorps Lgr5, anticorps LGR5

Sujet: LGR5/GPR49 is an orphan receptor. It may be an important receptor for signals controlling growth and differentiation of specific embryonic tissues.

Poids moléculaire: 99998

ID gène: 8549

NCBI Accession: NP_001264155, NP_003658

UniProt: O75473

Pathways: Signalisation WNT