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Ataxin 1 anticorps (AA 754-781)

ATXN1 Reactivité: Humain WB, IF Hôte: Lapin Polyclonal RB16258 unconjugated
N° du produit ABIN389309
  • Antigène Voir toutes Ataxin 1 (ATXN1) Anticorps
    Ataxin 1 (ATXN1)
    Épitope
    • 28
    • 20
    • 19
    • 11
    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 754-781
    Reactivité
    • 78
    • 60
    • 36
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 65
    • 47
    • 1
    Lapin
    Clonalité
    • 66
    • 47
    Polyclonal
    Conjugué
    • 43
    • 8
    • 7
    • 7
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp Ataxin 1 est non-conjugé
    Application
    • 85
    • 46
    • 35
    • 33
    • 32
    • 23
    • 23
    • 23
    • 9
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This ATXN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 754-781 amino acids from human ATXN1.
    Clone
    RB16258
    Isotype
    Ig Fraction
    Top Product
    Discover our top product ATXN1 Anticorps primaire
  • Indications d'application
    IF: 1:10~50. WB: 1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Date de péremption
    6 months
  • Antigène
    Ataxin 1 (ATXN1)
    Autre désignation
    ATXN1 (ATXN1 Produits)
    Synonymes
    anticorps ATX1, anticorps D6S504E, anticorps SCA1, anticorps ATXN1, anticorps ataxin 1b, anticorps atxn1, anticorps 2900016G23Rik, anticorps Atx1, anticorps C85907, anticorps ENSMUSG00000074917, anticorps Gm10786, anticorps Sca1, anticorps CG4547, anticorps Dmel\\CG4547, anticorps dAtx-1, anticorps dAtx1, anticorps sca1, anticorps ataxin 1, anticorps ataxin 1b, anticorps Ataxin 1, anticorps ATXN1, anticorps atxn1b, anticorps Atxn1, anticorps Atx-1
    Sujet
    The autosomal dominant cerebellar ataxias (ADCA) are a heterogeneous group of neurodegenerative disorders characterized by progressive degeneration of the cerebellum, brain stem and spinal cord. Clinically, ADCA has been divided into three groups: ADCA types I-III. ADCAI is genetically heterogeneous, with five genetic loci, designated spinocerebellar ataxia (SCA) 1, 2, 3, 4 and 6, being assigned to five different chromosomes. ADCAII, which always presents with retinal degeneration (SCA7), and ADCAIII often referred to as the `pure' cerebellar syndrome (SCA5), are most likely homogeneous disorders. Several SCA genes have been cloned and shown to contain CAG repeats in their coding regions. ADCA is caused by the expansion of the CAG repeats, producing an elongated polyglutamine tract in the corresponding protein. The expanded repeats are variable in size and unstable, usually increasing in size when transmitted to successive generations. The function of the ataxins is not known.
    Poids moléculaire
    86923
    ID gène
    6310
    NCBI Accession
    NP_000323, NP_001121636
    UniProt
    P54253
    Pathways
    Synaptic Membrane
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