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PIK3C3 anticorps (pSer676)

PIK3C3 Reactivité: Humain DB Hôte: Lapin Polyclonal RB11905 unconjugated
N° du produit ABIN389757
  • Antigène Voir toutes PIK3C3 Anticorps
    PIK3C3 (Phosphoinositide-3-Kinase, Class 3 (PIK3C3))
    Épitope
    • 26
    • 22
    • 22
    • 16
    • 13
    • 12
    • 12
    • 10
    • 8
    • 8
    • 7
    • 7
    • 7
    • 7
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer676
    Reactivité
    • 200
    • 61
    • 55
    • 3
    • 1
    Humain
    Hôte
    • 198
    • 2
    Lapin
    Clonalité
    • 191
    • 9
    Polyclonal
    Conjugué
    • 54
    • 22
    • 21
    • 20
    • 17
    • 16
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp PIK3C3 est non-conjugé
    Application
    • 160
    • 113
    • 95
    • 40
    • 39
    • 30
    • 22
    • 18
    • 17
    • 16
    • 15
    • 9
    • 1
    • 1
    • 1
    • 1
    Dot Blot (DB)
    Homologie
    M, Pig, Rat, X
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This PI3KC3 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S676 of human PI3KC3.
    Clone
    RB11905
    Isotype
    Ig Fraction
    Top Product
    Discover our top product PIK3C3 Anticorps primaire
  • Indications d'application
    DB: 1:500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Date de péremption
    6 months
  • Antigène
    PIK3C3 (Phosphoinositide-3-Kinase, Class 3 (PIK3C3))
    Autre désignation
    PI3KC3 (PIK3C3 Produits)
    Synonymes
    anticorps im:7147158, anticorps wu:fc13g06, anticorps wu:fz51e12, anticorps zgc:112016, anticorps zgc:113009, anticorps VPS34, anticorps hVps34, anticorps 5330434F23Rik, anticorps Vps34, anticorps phosphatidylinositol 3-kinase catalytic subunit type 3, anticorps phosphatidylinositol 3-kinase catalytic subunit type 3 L homeolog, anticorps phosphatidylinositol 3-kinase, catalytic subunit type 3, anticorps PIK3C3, anticorps pik3c3.L, anticorps pik3c3, anticorps Pik3c3
    Sujet
    PI3KC3 is a catalytic subunit of the PI3K complex involved in the transport of lysosomal enzyme precursors to lysosomes. This enzyme acts catalytically to convert 1-phosphatidyl-1D-myo-inositol to 1-phosphatidyl-1D-myo-inositol 3-phosphate. Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). The regulation of the Beclin 1-PI3KC3 complex lipid kinase activity is a critical element in the autophagy signaling pathway.
    Poids moléculaire
    101549
    ID gène
    5289
    NCBI Accession
    NP_002638
    UniProt
    Q8NEB9
    Pathways
    AMPK Signaling, Activation of Innate immune Response, Inositol Metabolic Process, Toll-Like Receptors Cascades, Autophagy
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