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WISP3 anticorps (AA 305-335)

WISP3 Reactivité: Humain WB, IHC (p) Hôte: Lapin Polyclonal RB2145-2146 unconjugated
N° du produit ABIN390189
  • Antigène Voir toutes WISP3 Anticorps
    WISP3 (Wnt1 Inducible Signaling Pathway Protein 3 (WISP3))
    Épitope
    • 15
    • 6
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 305-335
    Reactivité
    • 24
    • 16
    • 2
    Humain
    Hôte
    • 38
    • 1
    Lapin
    Clonalité
    • 39
    Polyclonal
    Conjugué
    • 10
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp WISP3 est non-conjugé
    Application
    • 29
    • 16
    • 13
    • 13
    • 9
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogène
    This WISP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 305-335 amino acids from the Central region of human WISP3.
    Clone
    RB2145-2146
    Isotype
    Ig Fraction
    Top Product
    Discover our top product WISP3 Anticorps primaire
  • Indications d'application
    WB: 1:1000. IHC-P: 1:50~100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Date de péremption
    6 months
  • Ji, Jia, Jia, Ji, Hargest, Jiang: "WISP-2 in human gastric cancer and its potential metastatic suppressor role in gastric cancer cells mediated by JNK and PLC-? pathways." dans: British journal of cancer, Vol. 113, Issue 6, pp. 921-33, (2015) (PubMed).

  • Antigène
    WISP3 (Wnt1 Inducible Signaling Pathway Protein 3 (WISP3))
    Autre désignation
    WISP3 (WISP3 Produits)
    Synonymes
    anticorps CCN6, anticorps LIBC, anticorps PPAC, anticorps PPD, anticorps ENSMUSG00000062074, anticorps Gm735, anticorps WISP-3, anticorps RGD1564120, anticorps WISP3, anticorps si:dkey-119m7.6, anticorps WNT1 inducible signaling pathway protein 3, anticorps WISP3, anticorps Wisp3, anticorps wisp3
    Sujet
    WISP3 is a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like domain. WISP3 is overexpressed in colon tumors. It may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. Mutations of the WISP3 gene are associated with progressive pseudorheumatoid dysplasia, an autosomal recessive skeletal disorder, indicating that the gene is essential for normal postnatal skeletal growth and cartilage homeostasis.
    Poids moléculaire
    39293
    ID gène
    8838
    NCBI Accession
    NP_003871, NP_937882
    UniProt
    O95389
    Pathways
    Signalisation WNT, Growth Factor Binding
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