PARP6 anticorps (C-Term)

N° du produit ABIN390248

Détail du produit anti-PARP6 anticorps

Antigène: PARP6 (Poly (ADP-Ribose) Polymerase Family, Member 6 (PARP6))

Épitope: AA 508-538, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PARP6 est non-conjugé

Application: Western Blotting (WB)

Homologie: M

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This Parp6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 508-538 amino acids from the C-terminal region of human Parp6.

Clone: RB14170

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur PARP6

Antigène: PARP6 (Poly (ADP-Ribose) Polymerase Family, Member 6 (PARP6))

Autre désignation: Parp6 (PARP6 Produits)

Synonymes: anticorps ARTD17, anticorps PARP-6-B1, anticorps PARP-6-C, anticorps pART17, anticorps 1700119G14Rik, anticorps 2310028P13Rik, anticorps 3110038K10Rik, anticorps C030013N01Rik, anticorps PARP-6, anticorps RGD1310937, anticorps zgc:92798, anticorps poly(ADP-ribose) polymerase family member 6, anticorps poly (ADP-ribose) polymerase family, member 6, anticorps poly(ADP-ribose) polymerase family member 6 S homeolog, anticorps poly [ADP-ribose] polymerase 6, anticorps poly (ADP-ribose) polymerase family, member 6a, anticorps PARP6, anticorps Parp6, anticorps parp6, anticorps parp6.S, anticorps LOC100475149, anticorps parp6a

Sujet: Poly(ADP-ribosyl)ation is an immediate DNA-damage-dependent post-translational modification of histones and other nuclear proteins that contributes to the survival of injured proliferating cells. Poly(ADP-ribose) polymerases (PARPs) now constitute a large family of 18 proteins, encoded by different genes and displaying a conserved catalytic domain in which PARP-1 (113 kDa), the founding member, and PARP-2 (62 kDa) are so far the sole enzymes whose catalytic activity has been shown to be immediately stimulated by DNA strand breaks. A large repertoire of sequences encoding novel PARPs now extends considerably the field of poly(ADP-ribosyl)ation reactions to various aspects of the cell biology including cell proliferation and cell death. Some of these new members interact with each other, share common partners and common subcellular localizations suggesting possible fine tuning in the regulation of this post-translational modification of proteins.

Poids moléculaire: 71115

ID gène: 56965

NCBI Accession: NP_064599

UniProt: Q2NL67