Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

AD_K2 (AA 633-660), (C-Term) anticorps

Reactivité: Humain, Singe, Souris WB Hôte: Lapin Polyclonal RB00896 unconjugated
N° du produit ABIN390986
  • Antigène
    AD_K2
    Épitope
    AA 633-660, C-Term
    Reactivité
    Humain, Singe, Souris
    Hôte
    Lapin
    Clonalité
    Polyclonal
    Application
    Western Blotting (WB)
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogène
    This AD_K2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 633-660 amino acids from the C-terminal region of human AD_K2.
    Clone
    RB00896
    Isotype
    Ig Fraction
  • Indications d'application
    WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Date de péremption
    6 months
  • Billard, Fitzhugh, Parker, Brozowski, McGinnis, Timoshchenko, Serafin, Lininger, Klauber-Demore, Sahagian, Truong, Sassano, Serody, Tarrant: "G Protein Coupled Receptor Kinase 3 Regulates Breast Cancer Migration, Invasion, and Metastasis." dans: PLoS ONE, Vol. 11, Issue 4, pp. e0152856, (2016) (PubMed).

    Rao, Rapoport, Kim: "Decreased GRK3 but not GRK2 expression in frontal cortex from bipolar disorder patients." dans: The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP), Vol. 12, Issue 6, pp. 851-60, (2009) (PubMed).

  • Antigène
    AD_K2
    Sujet
    The beta-adrenergic receptor kinase specifically phosphorylates the agonist-occupied form of the beta-adrenergic and related G protein-coupled receptors. Overall, the ADRBK2 enzyme, also known as GRK3, has 85 % amino acid similarity with ADRBK1, with the protein kinase catalytic domain having 95 % similarity. The ADRBK2 mRNA is approximately 8 kilobases with a distribution similar to that of ADRBK1. These data suggest the existence of a family of receptor kinases which may serve broadly to regulate receptor function.
    Poids moléculaire
    79710
    ID gène
    157
    NCBI Accession
    NP_005151
    UniProt
    P35626
Vous êtes ici:
Support technique