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CDKL5 anticorps (C-Term)

CDKL5 Reactivité: Humain WB, IHC (p) Hôte: Lapin Polyclonal RB3556 unconjugated
N° du produit ABIN391362
  • Antigène Voir toutes CDKL5 Anticorps
    CDKL5 (Cyclin-Dependent Kinase-Like 5 (CDKL5))
    Épitope
    • 15
    • 15
    • 8
    • 8
    • 6
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 982-1012, C-Term
    Reactivité
    • 50
    • 34
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 62
    • 1
    Lapin
    Clonalité
    • 62
    • 1
    Polyclonal
    Conjugué
    • 17
    • 7
    • 6
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CDKL5 est non-conjugé
    Application
    • 53
    • 34
    • 14
    • 13
    • 13
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogène
    This CDKL5 (STK9) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 982-1012 amino acids from the C-terminal region of human CDKL5 (STK9).
    Clone
    RB3556
    Isotype
    Ig Fraction
  • Indications d'application
    WB: 1:1000. IHC-P: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Date de péremption
    6 months
  • Antigène
    CDKL5 (Cyclin-Dependent Kinase-Like 5 (CDKL5))
    Autre désignation
    CDKL5 (STK9) (CDKL5 Produits)
    Synonymes
    anticorps issx, anticorps stk9, anticorps EIEE2, anticorps ISSX, anticorps STK9, anticorps BC038161, anticorps Stk9, anticorps cyclin dependent kinase like 5, anticorps cyclin-dependent kinase-like 5, anticorps CDKL5, anticorps cdkl5, anticorps Cdkl5
    Sujet
    Defects in STK9, a dual-specificity serine/threonine kinase, are a cause of atypical Rett syndrome. Rett syndrome is an X-linked dominant disease. It is a progressive neurologic developmental disorder and one of the most common causes of mental retardation in females. Patients appear to develop normally until 6 to 18 months of age, then gradually lose speech and purposeful hand movements and develop microcephaly, seizures, autism, ataxia, intermittent hyperventilation, and stereotypic hand movements. After initial regression, the condition stabilizes and patients usually survive into adulthood. Rett syndrome due to CDKL5-associated mutations is characterized by a severe early-onset phenotype and atypical features such as infantile spasms.
    Poids moléculaire
    107519
    ID gène
    6792
    NCBI Accession
    NP_001032420, NP_003150
    UniProt
    O76039
    Pathways
    Regulation of Cell Size
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