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MME anticorps (C-Term)

Name: MME anticorps (C-Term)
SKU: ABIN391499
Price: 475.5 EUR
Availability: InStock

MME Reactivité: Humain FACS, WB, IHC (p) Hôte: Lapin Polyclonal RB18821 unconjugated

Western blot analysis of Neprilysin Antibody (C-term) (ABIN391499 and ABIN2841464) in ,,Ramos cell line lysates (35 μg/lane).

Neprilysin Antibody (C-term) (ABIN391499 and ABIN2841464) flow cytometry analysis of Ramos cells (bottom histogram) compared to a negative control cell (top histogram).

FACS

Formalin-fixed and paraffin-embedded human kidney carcinoma with Neprilysin Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.

IHC (p)

3 images

N° du produit ABIN391499

Fiche de données

Antigène Voir toutes MME Anticorps

MME (Membrane Metallo-Endopeptidase (MME))
Épitope
16

13

10

8

7

7

7

7

7

6

5

4

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1
AA 506-534, C-Term
Reactivité
212

58

50

3

2

2

2

2

2

1

1

1

1
Humain
Hôte
109

109

2
Lapin
Anticorps secondaires appropriés
Clonalité
115

104

2
Polyclonal
Conjugué
107

19

19

14

9

6

5

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Cet anticorp MME est non-conjugé
Application
131

100

80

69

38

29

21

21

13

13

10

8

6

5

5

3

2

2

1

1

1

1

1
Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie

M, Rb, Rat

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène

This Neprilysin antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 506-534 amino acids from the C-terminal region of human Neprilysin.

Clone

RB18821

Isotype

Ig Fraction

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anti-Membrane Metallo-Endopeptidase (MME) (AA 286-428) antibody
MME Reactivité: Rat WB, IHC, IP, ICC Hôte: Lapin Polyclonal unconjugated

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anti-Membrane Metallo-Endopeptidase (MME) (AA 549-750) antibody
MME Reactivité: Humain FACS, WB, IHC, ELISA, ICC, Neut Hôte: Souris Monoclonal 6G12E12 unconjugated

anti-Membrane Metallo-Endopeptidase (MME) (AA 297-483) antibody
MME Reactivité: Humain WB, IHC, ELISA, StM, Coat Hôte: Souris Monoclonal MME-1892 unconjugated

anti-Membrane Metallo-Endopeptidase (MME) (AA 52-750) antibody
MME Reactivité: Humain, Souris, Rat WB, IHC (p) Hôte: Lapin Polyclonal unconjugated

Indications d'application

WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions

For Research Use only
Format

Liquid

Buffer

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur

Sodium azide

Précaution d'utilisation

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock

4 °C,-20 °C

Stockage commentaire

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption

6 months
Antigène

MME (Membrane Metallo-Endopeptidase (MME))

Autre désignation

Neprilysin (MME Produits)

Synonymes

anticorps CALLA, anticorps CD10, anticorps NEP, anticorps SFE, anticorps 6030454K05Rik, anticorps C85356, anticorps Nep, anticorps neprilysin, anticorps membrane metalloendopeptidase, anticorps membrane metallo endopeptidase, anticorps membrane metallo-endopeptidase, anticorps MME, anticorps Mme

Classe de substances

Chemical

Sujet

MME is a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). This protein is present on leukemic cells of pre-B phenotype, which represent 85 % of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. It is a oprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin.

Poids moléculaire

85514

ID gène

4311

NCBI Accession

NP_000893, NP_009218, NP_009219, NP_009220

UniProt

P08473

Pathways

Signalisation RTK, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration