VRK1 anticorps (AA 366-396)

N° du produit ABIN391605

Détail du produit anti-VRK1 anticorps

Antigène: VRK1 (Vaccinia Related Kinase 1 (VRK1))

Épitope: AA 366-396

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp VRK1 est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This VRK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 366-396 amino acids from the Central region of human VRK1.

Clone: RB2997

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur VRK1

Antigène: VRK1 (Vaccinia Related Kinase 1 (VRK1))

Autre désignation: VRK1 (VRK1 Produits)

Synonymes: anticorps vrk1, anticorps MGC64390, anticorps MGC75762, anticorps VRK1, anticorps PCH1, anticorps PCH1A, anticorps 51PK, anticorps wu:fe16f06, anticorps zgc:56266, anticorps vaccinia related kinase 1 L homeolog, anticorps vaccinia related kinase 1, anticorps Serine/threonine-protein kinase VRK1, anticorps vrk1.L, anticorps vrk1, anticorps VRK1, anticorps vrk-1, anticorps Vrk1

Sujet: This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. This gene is widely expressed in human tissues and has increased expression in actively dividing cells, such as those in testis, thymus, fetal liver, and carcinomas. Its protein localizes to the nucleus and has been shown to promote the stability and nuclear accumulation of a transcriptionally active p53 Molecule and, in vitro, to phosphorylate Thr18 of p53 and reduce p53 ubiquitination. This gene, therefore, may regulate cell proliferation. This protein also phosphorylates histone, casein, and the transcription factors ATF2 (activating transcription factor 2) and c-JUN.

Poids moléculaire: 45476

ID gène: 7443

NCBI Accession: NP_003375

UniProt: Q99986