ADAMTS13 anticorps (AA 829-858)

N° du produit ABIN391641

Détail du produit anti-ADAMTS13 anticorps

Antigène: ADAMTS13 (ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 13 (ADAMTS13))

Épitope: AA 829-858

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ADAMTS13 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This ADAMTS13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 829-858 amino acids from the Central region of human ADAMTS13.

Clone: RB18029

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:500

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur ADAMTS13

Antigène: ADAMTS13 (ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 13 (ADAMTS13))

Autre désignation: ADAMTS13 (ADAMTS13 Produits)

Synonymes: anticorps ADAMTS13, anticorps ADAM-TS13, anticorps ADAMTS-13, anticorps C9orf8, anticorps VWFCP, anticorps vWF-CP, anticorps Gm710, anticorps ADAM metallopeptidase with thrombospondin type 1 motif 13, anticorps a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 13, anticorps ADAM metallopeptidase with thrombospondin type 1 motif, 13, anticorps ADAMTS13, anticorps Adamts13, anticorps adamts13

Sujet: ADAMTS13 is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme is the von Willebrand Factor (vWF)-cleaving protease, which is responsible for cleaving at the site of Tyr842-Met843 of the vWF molecule. A deficiency of this enzyme is associated with thrombotic thrombocytopenic purpura.

Poids moléculaire: 153604

ID gène: 11093

NCBI Accession: NP_620594, NP_620595, NP_620596

UniProt: Q76LX8