MAPK7 anticorps (C-Term)

N° du produit ABIN391722

Détail du produit anti-MAPK7 anticorps

Antigène: MAPK7 (Mitogen-Activated Protein Kinase 7 (MAPK7))

Épitope: AA 776-805, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAPK7 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: B, M, Rat

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This MAPK7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 776-805 amino acids from the C-terminal region of human MAPK7.

Clone: RB0919

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:50~100. IHC-P: 1:50~100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur MAPK7

Antigène: MAPK7 (Mitogen-Activated Protein Kinase 7 (MAPK7))

Autre désignation: ERK5 (MAPK7 Produits)

Synonymes: anticorps BMK1, anticorps ERK4, anticorps ERK5, anticorps PRKM7, anticorps Erk5-T, anticorps ATMPK7, anticorps F8D23.5, anticorps F8D23_5, anticorps MAP kinase 7, anticorps Bmk1, anticorps Erk5, anticorps Prkm7, anticorps ERK-5, anticorps bmk1, anticorps erk4, anticorps mapk7, anticorps prkm7, anticorps mitogen-activated protein kinase 7, anticorps MAP kinase 7, anticorps mitogen-activated protein kinase 7 L homeolog, anticorps MAPK7, anticorps Mapk7, anticorps MPK7, anticorps mapk7.L

Sujet: MEK5 and ERK5, a member of the MAP kinase subfamily of the Ser/Thr protein kinases, interact specifically with one another and not with MEK1/ERK1 or MEK2/ERK2 pathways. ERK5 is activated by tyrosine and threonine phosphorylation It is expressed in many adult tissues, abundantly in heart, placenta, lung, kidney and skeletal muscle, but is not detectable in liver. The second proline-rich region may interact with actin targeting the kinase to a specific location in the cell. ERK5 is autophosphorylated on threonine and tyrosine residues when the C-terminal part of the kinase, which could have a regulatory role, is absent.

Poids moléculaire: 88386

ID gène: 5598

NCBI Accession: NP_002740, NP_620601, NP_620602, NP_620603

UniProt: Q13164

Pathways: Signalisation MAPK, Neurotrophin Signaling Pathway, Activation of Innate immune Response, cAMP Metabolic Process, Toll-Like Receptors Cascades, Negative Regulation of intrinsic apoptotic Signaling