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RIPK3 anticorps (C-Term)

RIPK3 Reactivité: Humain, Souris WB, IHC (p) Hôte: Lapin Polyclonal RB3319 unconjugated
N° du produit ABIN392275
  • Antigène Voir toutes RIPK3 Anticorps
    RIPK3 (Receptor-Interacting serine-threonine Kinase 3 (RIPK3))
    Épitope
    • 10
    • 8
    • 8
    • 7
    • 7
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 489-518, C-Term
    Reactivité
    • 79
    • 42
    • 19
    • 6
    • 4
    • 4
    • 2
    • 1
    Humain, Souris
    Hôte
    • 82
    • 9
    Lapin
    Clonalité
    • 82
    • 9
    Polyclonal
    Conjugué
    • 46
    • 9
    • 8
    • 7
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp RIPK3 est non-conjugé
    Application
    • 84
    • 52
    • 44
    • 18
    • 11
    • 8
    • 6
    • 5
    • 4
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogène
    This RIPK3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 489-518 amino acids from the C-terminal region of human RIPK3.
    Clone
    RB3319
    Isotype
    Ig Fraction
    Top Product
    Discover our top product RIPK3 Anticorps primaire
  • Indications d'application
    WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid freeze-thaw cycles.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots.
    Date de péremption
    6 months
  • McCullough, McMullen, Das, Roychowdhury, Strainic, Medof, Nagy: "Differential contribution of complement receptor C5aR in myeloid and non-myeloid cells in chronic ethanol-induced liver injury in mice." dans: Molecular immunology, Vol. 75, pp. 122-32, (2017) (PubMed).

    Deutsch, Graffeo, Rokosh, Pansari, Ochi, Levie, Van Heerden, Tippens, Greco, Barilla, Tomkötter, Zambirinis, Avanzi, Gulati, Pachter, Torres-Hernandez, Eisenthal, Daley, Miller: "Divergent effects of RIP1 or RIP3 blockade in murine models of acute liver injury." dans: Cell death & disease, Vol. 6, pp. e1759, (2015) (PubMed).

    Dara, Johnson, Suda, Win, Gaarde, Han, Kaplowitz: "Receptor interacting protein kinase 1 mediates murine acetaminophen toxicity independent of the necrosome and not through necroptosis." dans: Hepatology (Baltimore, Md.), (2015) (PubMed).

    Roychowdhury, Chiang, Mandal, McMullen, Liu, Cohen, Pollard, Feldstein, Nagy: "Inhibition of apoptosis protects mice from ethanol-mediated acceleration of early markers of CCl4 -induced fibrosis but not steatosis or inflammation." dans: Alcoholism, clinical and experimental research, Vol. 36, Issue 7, pp. 1139-47, (2012) (PubMed).

    Zorde-Khvalevsky, Abramovitch, Barash, Spivak-Pohis, Rivkin, Rachmilewitz, Galun, Giladi: "Toll-like receptor 3 signaling attenuates liver regeneration." dans: Hepatology (Baltimore, Md.), Vol. 50, Issue 1, pp. 198-206, (2009) (PubMed).

  • Antigène
    RIPK3 (Receptor-Interacting serine-threonine Kinase 3 (RIPK3))
    Autre désignation
    RIPK3 (RIPK3 Produits)
    Synonymes
    anticorps RIPK3, anticorps RIP3, anticorps 2610528K09Rik, anticorps AW107945, anticorps Rip3, anticorps Hcyp2, anticorps receptor interacting serine/threonine kinase 3, anticorps receptor interacting serine/threonine kinase 3 S homeolog, anticorps receptor-interacting serine-threonine kinase 3, anticorps RIPK3, anticorps ripk3.S, anticorps Ripk3
    Sujet
    RIPK3 is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor.
    Poids moléculaire
    56887
    ID gène
    11035
    NCBI Accession
    NP_006862
    UniProt
    Q9Y572
    Pathways
    Activation of Innate immune Response, Toll-Like Receptors Cascades
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