TGFBR1 anticorps (AA 134-163)

N° du produit ABIN392279

Détail du produit anti-TGFBR1 anticorps

Antigène: TGFBR1 (Transforming Growth Factor, beta Receptor 1 (TGFBR1))

Épitope: AA 134-163

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TGFBR1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Homologie: B, M, Pig, Rat

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This TGF Beta Receptor I antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 134-163 amino acids from the Central region of human TGF Beta Receptor I.

Clone: RB03530

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze-thaw cycles.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots.

Date de péremption: 6 months

Références pour anticorps anti-TGFBR1 (ABIN392279)

Yi, Li, Nie, Jia, Zhang, Wang, Wang: "Effect of astragalus injection on renal tubular epithelial transdifferentiation in type 2 diabetic mice." dans: BMC complementary and alternative medicine, Vol. 16, pp. 222, (2017) (PubMed).

Zhang, Chang, Li, Gao, Wang, Ma, Li, Wang: "miR-140-5p regulates adipocyte differentiation by targeting transforming growth factor-β signaling." dans: Scientific reports, Vol. 5, pp. 18118, (2016) (PubMed).

Hou, Wu, Wei, Ren, Du, Wu, Li, Shi: "CD36 is involved in high glucose-induced epithelial to mesenchymal transition in renal tubular epithelial cells." dans: Biochemical and biophysical research communications, Vol. 468, Issue 1-2, pp. 281-6, (2015) (PubMed).

Miles, Tung, Aguiar, Kurtoglu, Sikes: "Increased TGF-?1-mediated suppression of growth and motility in castrate-resistant prostate cancer cells is consistent with Smad2/3 signaling." dans: The Prostate, Vol. 72, Issue 12, pp. 1339-50, (2012) (PubMed).

Détails sur TGFBR1

Antigène: TGFBR1 (Transforming Growth Factor, beta Receptor 1 (TGFBR1))

Autre désignation: TGF beta Receptor I (TGFBR1) (TGFBR1 Produits)

Synonymes: anticorps AAT5, anticorps ACVRLK4, anticorps ALK-5, anticorps ALK5, anticorps LDS1A, anticorps LDS2A, anticorps MSSE, anticorps SKR4, anticorps TGFR-1, anticorps aat5, anticorps acvrlk4, anticorps alk-5, anticorps alk5, anticorps lds1a, anticorps lds2a, anticorps skr4, anticorps tgfr-1, anticorps TGFBR1, anticorps x-trr1, anticorps AU017191, anticorps Alk-5, anticorps TbetaR-I, anticorps TbetaRI, anticorps Alk5, anticorps Skr4, anticorps Tgfr-1, anticorps tbetaR-I, anticorps tgfbr1, anticorps zgc:123263, anticorps transforming growth factor beta receptor 1, anticorps transforming growth factor beta receptor I, anticorps transforming growth factor beta receptor I S homeolog, anticorps transforming growth factor, beta receptor I, anticorps transforming growth factor, beta receptor 1, anticorps transforming growth factor, beta receptor 1 a, anticorps TGFBR1, anticorps tgfbr1, anticorps tgfbr1.S, anticorps Tgfbr1, anticorps tgfbr1a

Sujet: The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS).

Poids moléculaire: 55960

ID gène: 7046

NCBI Accession: NP_001124388, NP_004603

UniProt: P36897

Pathways: Growth Factor Binding