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MAP3K10 anticorps (C-Term)

MAP3K10 Reactivité: Humain WB, IHC (p) Hôte: Lapin Polyclonal RB0986 unconjugated
N° du produit ABIN392424
  • Antigène Voir toutes MAP3K10 Anticorps
    MAP3K10 (Mitogen-Activated Protein Kinase Kinase Kinase 10 (MAP3K10))
    Épitope
    • 13
    • 8
    • 7
    • 7
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 628-659, C-Term
    Reactivité
    • 49
    • 21
    • 9
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 46
    • 3
    Lapin
    Clonalité
    • 49
    Polyclonal
    Conjugué
    • 19
    • 6
    • 6
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp MAP3K10 est non-conjugé
    Application
    • 40
    • 33
    • 30
    • 7
    • 6
    • 6
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogène
    This MLK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 628-659 amino acids from the C-terminal region of human MLK2.
    Clone
    RB0986
    Isotype
    Ig Fraction
  • Indications d'application
    WB: 1:1000. IHC-P: 1:50~100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Date de péremption
    6 months
  • Humphrey, Newcomb, Yu, Hao, Yu, Krajewski, Du, Jhala: "Mixed lineage kinase-3 stabilizes and functionally cooperates with TRIBBLES-3 to compromise mitochondrial integrity in cytokine-induced death of pancreatic beta cells." dans: The Journal of biological chemistry, Vol. 285, Issue 29, pp. 22426-36, (2010) (PubMed).

    Nagao, Hayashi: "Mixed lineage kinase 2 and hippocalcin are localized in Lewy bodies of Parkinson's disease." dans: Journal of the neurological sciences, Vol. 281, Issue 1-2, pp. 51-4, (2009) (PubMed).

  • Antigène
    MAP3K10 (Mitogen-Activated Protein Kinase Kinase Kinase 10 (MAP3K10))
    Autre désignation
    MLK2 (MAP3K10 Produits)
    Synonymes
    anticorps MEKK10, anticorps MLK2, anticorps MST, anticorps BC028668, anticorps BC046514, anticorps Mlk2, anticorps mlk2, anticorps xmlk2, anticorps mitogen-activated protein kinase kinase kinase 10, anticorps mitogen activated protein kinase kinase kinase 10, anticorps mitogen-activated protein kinase kinase kinase 10 L homeolog, anticorps MAP3K10, anticorps Map3k10, anticorps map3k10.L
    Sujet
    MLK2 is a member of the serine/threonine kinase family. This kinase has been shown to activate MAPK8/JNK and MKK4/SEK1, and this kinase itself can be phoshorylated, and thus activated by JNK kinases. This kinase functions preferentially on the JNK signaling pathway, and is reported to be involved in nerve growth factor (NGF) induced neuronal apoptosis.
    Poids moléculaire
    103694
    ID gène
    4294
    NCBI Accession
    NP_002437
    UniProt
    Q02779
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