MST1 anticorps (C-Term)

N° du produit ABIN392427

Détail du produit anti-MST1 anticorps

Antigène: MST1 (Macrophage Stimulating 1 (Hepatocyte Growth Factor-Like) (MST1))

Épitope: AA 385-415, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MST1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: B

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This MST1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 385-415 amino acids from the C-terminal region of human MST1.

Clone: RB1193

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-MST1 (ABIN392427)

Attarha, Andersson, Mints, Souchelnytskyi: "Individualised proteome profiling of human endometrial tumours improves detection of new prognostic markers." dans: British journal of cancer, Vol. 109, Issue 3, pp. 704-13, (2013) (PubMed).

Ren, Yan, You, Sun: "Down-regulation of mammalian sterile 20-like kinase 1 by heat shock protein 70 mediates cisplatin resistance in prostate cancer cells." dans: Cancer research, Vol. 68, Issue 7, pp. 2266-74, (2008) (PubMed).

Détails sur MST1

Antigène: MST1 (Macrophage Stimulating 1 (Hepatocyte Growth Factor-Like) (MST1))

Autre désignation: MST1 (MST1 Produits)

Synonymes: anticorps D3F15S2, anticorps DNF15S2, anticorps HGFL, anticorps MSP, anticorps NF15S2, anticorps E2F2, anticorps D3F15S2h, anticorps D9H3F15S2, anticorps DNF15S2h, anticorps Hgfl, anticorps HGF1/MSP, anticorps E1A, anticorps XHL, anticorps d3f15s2, anticorps dnf15s2, anticorps hgfl, anticorps msp, anticorps mst1, anticorps nf15s2, anticorps macrophage stimulating 1, anticorps macrophage stimulating 1 (hepatocyte growth factor-like), anticorps serine/threonine kinase 4, anticorps macrophage stimulating 1 L homeolog, anticorps MST1, anticorps Mst1, anticorps STK4, anticorps mst1.L

Sujet: MST1 is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein kinase cascade. The encoded protein can phosphorylate myelin basic protein and undergoes autophosphorylation. A caspase-cleaved fragment of the encoded protein has been shown to be capable of phosphorylating histone H2B. The particular phosphorylation catalyzed by this protein has been correlated with apoptosis, and it is possible that this protein induces the chromatin condensation observed in this process.

Poids moléculaire: 55630

ID gène: 6789

NCBI Accession: NP_006273

UniProt: Q13043