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PRKG1 anticorps (C-Term)

PRKG1 Reactivité: Humain, Souris WB, IHC (p) Hôte: Lapin Polyclonal RB1046 unconjugated
N° du produit ABIN392536
  • Antigène Voir toutes PRKG1 Anticorps
    PRKG1 (Protein Kinase, CGMP-Dependent, Type I (PRKG1))
    Épitope
    • 8
    • 7
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    AA 629-660, C-Term
    Reactivité
    • 42
    • 26
    • 13
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain, Souris
    Hôte
    • 36
    • 6
    Lapin
    Clonalité
    • 38
    • 4
    Polyclonal
    Conjugué
    • 24
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp PRKG1 est non-conjugé
    Application
    • 35
    • 24
    • 16
    • 6
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Homologie
    B
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This cGKI (cGKI beta) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 629-660 amino acids from the C-terminal region of human cGKI beta.
    Clone
    RB1046
    Isotype
    Ig Fraction
  • Indications d'application
    WB: 1:1000. WB: 1:1000. IHC-P: 1:100. IHC-P: 1:100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Date de péremption
    6 months
  • Schwappacher, Kilic, Kojonazarov, Lang, Diep, Zhuang, Gawlowski, Schermuly, Pfeifer, Boss, Pilz: "A molecular mechanism for therapeutic effects of cGMP-elevating agents in pulmonary arterial hypertension." dans: The Journal of biological chemistry, Vol. 288, Issue 23, pp. 16557-66, (2013) (PubMed).

  • Antigène
    PRKG1 (Protein Kinase, CGMP-Dependent, Type I (PRKG1))
    Autre désignation
    cGKI (cGKI beta) (PRKG1 Produits)
    Synonymes
    anticorps prkg1, anticorps zgc:63955, anticorps Pkgi, anticorps cGk1, anticorps 1, anticorps PKG, anticorps PRKG1B, anticorps PRKGR1B, anticorps cGK, anticorps cGK 1, anticorps cGK1, anticorps cGKI, anticorps cGKI-BETA, anticorps cGKI-alpha, anticorps CGKI, anticorps cGKI-beta, anticorps AW125416, anticorps Gm19690, anticorps Prkg1b, anticorps Prkgr1b, anticorps Prkg1beta, anticorps protein kinase, cGMP-dependent, type Ia, anticorps protein kinase, cGMP-dependent, type I, anticorps protein kinase, cGMP-dependent, type 1, anticorps prkg1a, anticorps PRKG1, anticorps prkg1, anticorps Prkg1
    Sujet
    Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.
    Poids moléculaire
    76364
    ID gène
    5592
    NCBI Accession
    NP_001091982, NP_006249
    UniProt
    Q13976
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